Five items differentiate mild to severe dementia from normal to minimal cognitive impairment—Using the Global Deterioration Scale

Yoon Jung Choi MD , Chang Won Won MD, PhD , Sunyoung Kim MD , Hyun Rim Choi MD, PhD , Byung Sung Kim MD, PhD , Seung Youn Jeon MD , Sang Yun Kim MD, PhD , Kun Woo Park MD
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引用次数: 9

Abstract

Background/Purpose

The aim of our study is to develop a concise and effective dementia screening tool for use in primary care, wherein we selected five items from the Global Deterioration Scale (GDS) that were most predictive of dementia diagnosis.

Methods

Our study population comprised 191 patients older than 60 years who visited four university hospitals between 2008 and 2011 for impaired memory or medical care. Our 5-item screening tool is an abbreviated version of the GDS. We compared the assessment results obtained through our model with those obtained through the GDS in order to evaluate the accuracy of our tool in detecting dementia.

Results

The screening tool had a sensitivity of 91.2%, specificity of 75.0%, a cutoff value of 12.495, and an area under the curve of 0.911 (95% confidence interval, 0.862–0.948; p < 0.05).

Conclusion

We anticipate that our abridged GDS, composed of five items, will facilitate a rapid, yet effective assessment of patients in primary care centers. Its use will benefit both patients and medical professionals by minimizing the length of time required to conduct the assessment, and by allowing early diagnosis and care of patients. However, further research with a larger population is required to verify its efficacy.

区分轻度至重度痴呆与正常至轻度认知障碍的五个项目——使用全球恶化量表
背景/目的我们研究的目的是开发一种简洁有效的痴呆症筛查工具,用于初级保健,其中我们从全球恶化量表(GDS)中选择了五个最能预测痴呆症诊断的项目。方法我们的研究人群包括191名60岁以上的患者,他们在2008年至2011年间访问了四所大学医院,接受记忆受损或医疗护理。我们的5项筛选工具是GDS的缩写版本。我们将通过我们的模型获得的评估结果与通过GDS获得的结果进行了比较,以评估我们的工具在检测痴呆症方面的准确性。结果该筛查工具的敏感性为91.2%,特异性为75.0%,截止值为12.495,曲线下面积为0.911(95%置信区间,0.862–0.948;p<;0.05)。它的使用将最大限度地缩短进行评估所需的时间,并允许对患者进行早期诊断和护理,从而使患者和医疗专业人员都受益。然而,还需要对更多的人群进行进一步的研究来验证其疗效。
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