Impact of serum magnesium levels in critically ill elderly patients—A study in a rural teaching hospital

Sunil Kumar MD, PGDGM , Shraddha Jain MS , Sachin Agrawal MD, PGDGM , Akshay Honmode MD
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引用次数: 14

Abstract

Background/Purpose

Magnesium deficiency has been a common, but easily ignored, electrolyte abnormality. Studies on magnesium deficiency are lacking in India, especially in a rural setting. Here, we have correlated serum magnesium levels with outcomes in elderly patients admitted to the medical intensive care unit with respect to the length of intensive care unit stay, need for mechanical ventilatory support and its duration, and outcome (discharge/death).

Methods

A prospective, observational study was conducted in patients aged 60 years and older, who had been admitted to the intensive care unit of the medicine department for over a year. The chi-square test was applied to correlate hypomagnesemia with the outcome.

Results

In our study, 59.30% of the elderly patients had hypomagnesemia. Compared with patients with a normal magnesium level, hypomagnesemic patients had no correlation with the duration of medical intensive care unit stay (5.57 ± 6.10 days vs. 5.61 ± 5.55 days), but the need for mechanical ventilation (57.84% vs. 45.71%), rate of discharge from the intensive care unit or cure (60.28% vs. 71.42% ), rate of death (39.21% vs. 28.57%), and mean duration of ventilation (3.07 ± 5.05 days vs. 2.15 ± 3.46 days) were higher. However, no significant statistical difference was found between these groups.

Conclusion

Hypomagnesemia was associated with a slightly higher mortality rate. Requirement and duration of ventilatory support were also higher, although not statistically significant. Hypomagnesemia was not found to have any impact on the duration of medical intensive care unit stay. Monitoring of serum magnesium levels may have prognostic and perhaps therapeutic implications in the elderly.

危重老年患者血清镁水平的影响——以某农村教学医院为例
背景/目的镁缺乏是一种常见但容易被忽视的电解质异常。印度缺乏对镁缺乏症的研究,尤其是在农村地区。在这里,我们将入住医疗重症监护室的老年患者的血清镁水平与重症监护室住院时间、机械通气支持的需要及其持续时间和结果(出院/死亡)的结果进行了相关性研究,他在内科重症监护室住了一年多。卡方检验用于将低镁血症与结果相关联。结果59.30%的老年患者存在低镁血症。与镁水平正常的患者相比,低镁血症患者与医疗重症监护室的住院时间(5.57±6.10天vs.5.61±5.55天)无关,但与机械通气的需要(57.84%vs.45.71%)、重症监护室出院率或治愈率(60.28%vs.71.42%)、死亡率(39.21%vs.28.57%)无关,平均通气时间(3.07±5.05天vs.2.15±3.46天)更高。然而,这些组之间没有发现显著的统计学差异。结论低镁血症的死亡率略高。通气支持的需求和持续时间也更高,尽管没有统计学意义。低镁血症对重症监护室的住院时间没有任何影响。监测血清镁水平可能对老年人具有预后和治疗意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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