Microwave induced facile synthesis and characterization of ZnO nanoparticles as efficient antibacterial agents

Dheeraj Singh Chauhan , C.S.A. Gopal , D. Kumar , N. Mahato , M.A. Quraishi , M.H. Cho
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引用次数: 16

Abstract

Microwave assisted synthesis of ZnO nanoparticles was performed at varying pH of the synthesis medium. At pH 8 and 10, uniform and crystalline ZnO nanoparticles were formed whereas at pH 6, layered basic zinc acetate (LBZA) was obtained. The present work proposes a new strategy to synthesize LBZA via microwave irradiation method. As-prepared ZnO nanoparticles were used to study antibacterial behavior against pathogenic Gram-negative and Gram-positive bacteria viz. E. coli, P. aeruginosa, S. aureus and E. faecalis under dark condition. The results show a significant decrease in viability of pathogenic bacterial cells with increase in interaction time with ZnO nanoparticles.

Abstract Image

微波诱导ZnO纳米颗粒的合成及其高效抗菌性能研究
在合成介质的不同pH下进行ZnO纳米颗粒的微波辅助合成。在pH 8和10下,形成均匀且结晶的ZnO纳米颗粒,而在pH 6下,获得层状碱性乙酸锌(LBZA)。本工作提出了一种通过微波辐射法合成LBZA的新策略。使用所制备的ZnO纳米颗粒研究了在黑暗条件下对致病性革兰氏阴性菌和革兰氏阳性菌(即大肠杆菌、铜绿假单胞菌、金黄色葡萄球菌和粪大肠杆菌)的抗菌行为。结果表明,随着与ZnO纳米颗粒相互作用时间的增加,病原细菌细胞的活力显著降低。
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