{"title":"Hépatites d'étiologie inconnue","authors":"I Chemin , P Merle , R Parana , C Trepo","doi":"10.1016/j.emchep.2004.01.001","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":100427,"journal":{"name":"EMC - Hépatologie","volume":"1 1","pages":"1-8"},"PeriodicalIF":0.0000,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.emchep.2004.01.001","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"EMC - Hépatologie","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1638622104000053","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
病因不明的肝炎
病因不明的肝炎,即所谓的隐源性肝炎,可能导致严重的肝损伤。其流行率在已发表的研究中差异很大。它的诊断主要基于对已知病因实体的排除,这些病因实体仍然非常异质。可能涉及自身免疫的非典型病例,尤其是自身抗体血清阴性或未知病毒感染。病毒学分子生物学技术的改进导致在过去90年代鉴定出新的嗜肝病毒,如GBV/C或TTV。然而,它们的肝脏致病性仍然存疑。最近在2000-2001年,发现了新的病毒制剂,如TTV变体、TLMV、Yonban、Sanban和SEN-V,但它们在肝病中的作用仍然值得怀疑。此外,几项研究强调了隐性HBV和HCV感染的存在,这些感染是目前商用诊断测试无法检测到的。在不久的将来,病毒学和相关临床流行病学研究的进展都很可能确定与隐源性肝炎有关的新病毒制剂。这将允许采用新的治疗方法来改善疾病的预后。
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