Utilidad de escalas pronósticas en hemorragia digestiva proximal secundaria a úlcera péptica

Griselda Martínez Ramírez, Marco Antonio Manrique, Miguel Ángel Chávez García, Nora Noemí Hernández Velázquez, Ernesto Pérez Valle, Teófilo Pérez Corona, María Guadalupe Martínez Galindo, Elvia Janeth Rubalcaba Macías, Alberto Antonio Cisneros, Darío Fernando Burbano Luna, Juan Manuel Gómez Urrutia, Jony Cerna Cardona, Jaime Gilberto Santamaría Sánchez
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引用次数: 0

Abstract

Introduction

Upper gastrointestinal bleeding (UGIB) is the most common gastrointestinal emergency, and a frequent cause of admission to the emergency services. It has a high mortality and morbidity, and is also one of the main indications for conducting an upper gastrointestinal endoscopy. Early risk stratification is made using prognostic scales that evaluate patients with high and low risk, and help make initial decisions, for the appropriate therapies that can save the lives of patients. The validated scales include Blatchford, Rockall, AIMS-65, and Forrest, are useful in predicting mortality, recurrence of the UGIB, cost, length of hospital stay, use of blood and endoscopic haemostasis.

Objective

To assess the usefulness of the Blatchford, Rockall, AIMS-65, and Forrest prognostic scales in patients with UGIB secondary to a peptic ulcer as predictors of mortality, recurrence of bleeding, hospital stay, use of blood, and endoscopic haemostasis.

Material and methods

The study included patients with a diagnosis of UGIB secondary to peptic ulcer admitted to the emergency department of the Juarez Hospital of Mexico during the period March 2013 to March 2015. The prognosis was estimated using the Rockall, Blatchford, AIMS-65, and Forrest scales.

Results

A total of 70 patients with UGIB secondary to peptic ulcer were included. Descriptive analysis of quantitative variables and analysis of variance using Fisher test were performed using Statistics Software 8. Using the Forrest classification, the endoscopic findings included, 1 a (4.28%), lb (12.85%), lla (10%), llb (14.2%), llc (8.57%), and III (50%) were observed in the endoscopic findings. Of the 40% (28) that received endoscopic therapy, there was re-bleeding in 3 (4.2%) patients during hospitalisation, and 1.42% died. The mean hospital stay was 3.74 days and a mean number of 1.11 packed red cells were transfused. Statistically significant relationships were observed in the Rockall scale to predict recurrence of UGIB (P=.019), in the Blatchford scale for UGIB recurrence (P=.063), mortality (P=.00004), need for transfusion (P=.0094), length of hospital stay (P=.0070), and in the Forrest scale as a predictor of a need for endoscopic treatment (P=.0000).

Conclusions

In our study Blatchford scale is the most useful for assessing recurrent bleeding, hospital stay, need for transfusion, and mortality. The Forrest scale is the only one that assesses the need for endoscopic therapy in patients with upper gastrointestinal bleeding secondary to peptic ulcer.

预后评分在消化性溃疡继发近端消化道出血中的应用
上消化道出血(UGIB)是最常见的胃肠道急诊,也是急诊入院的常见原因。它具有很高的死亡率和发病率,也是进行上消化道内窥镜检查的主要适应症之一。早期风险分层是使用预后量表进行的,该量表评估高风险和低风险患者,并有助于做出初步决定,以选择可以挽救患者生命的适当疗法。经验证的量表包括Blatchford、Rockall、AIMS-65和Forrest,可用于预测死亡率、UGIB复发、费用、住院时间、血液使用和内镜止血。目的评估Blatchford、Rockall、AIMS-65和Forrest预后量表在消化性溃疡继发UGIB患者中作为死亡率、出血复发、住院时间、血液使用和内镜止血预测指标的有用性。材料和方法该研究包括2013年3月至2015年3月期间在墨西哥华雷斯医院急诊科入院的诊断为消化性溃疡继发性UGIB的患者。使用Rockall、Blatchford、AIMS-65和Forrest量表评估预后。结果共纳入70例消化性溃疡继发UGIB患者。使用统计学软件8进行定量变量的描述性分析和使用Fisher检验的方差分析。使用Forrest分类,内镜检查结果包括:1 a(4.28%)、lb(12.85%)、lla(10%)、llb(14.2%)、llc(8.57%)和III(50%)。在接受内镜治疗的40%(28)患者中,有3名(4.2%)患者在住院期间再次出血,1.42%的患者死亡。平均住院时间为3.74天,平均输注1.11个红细胞。在Rockall量表中观察到预测UGIB复发的统计学显著关系(P=.019),在Blatchford量表中预测UGIB的复发(P=.063),死亡率(P=00004),需要输血(P=.0094),住院时间(P=.0070),以及在Forrest量表中作为需要内镜治疗的预测因素(P=0.000)。结论在我们的研究中,Blatchford量表对评估复发性出血、住院时间、输血需求和死亡率最有用。Forrest量表是唯一一个评估消化性溃疡继发上消化道出血患者是否需要内镜治疗的量表。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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