Tumores neuroendocrinos enteropancreáticos: diagnóstico y evaluación por ultrasonidoendoscópico; análisis de 5 años en el servicio de endoscopia del hospital de especialidades CMN Siglo XXI

Abstract

Objective

To Report the experience in the evaluation and diagnosis of gastro-enteropancreatic neuroendocrine tumours (GEP-NET) using endoscopic ultrasound (EUS) in the Endoscopy unit of the Mexican 21^st Century National Medical Centre (NMC XXIC).

Justification

The GEP-NET is a group of neoplasms of low incidence and prevalence neoplasms, but unfortunately there is no statistical records of these. EUS is a diagnostic tool in our unit, and we believe that our experience in this Department with these tumours should be reported.

Material and methods

A review was carried out using the Endoscopy Unit EUS procedures database for the period from 2008 to 2012. A total of 51 patients were found who were referred with a suspected diagnosis of GEP-NET.

Results

Out of a total of 21 patients with a diagnosis confirmed by fine needle aspirate (FNA) biopsy, 13 were women (61.9%) and 8 were men (38%). The mean age was 52 years, with a range of 12-81 years. The location of the tumours was in the pancreas in 12 (57.1%) cases, in the stomach in 4 (19%) cases (19%), the duodenum in 3 (14.2%) cases, in the retroperitoneum in 2 (9.5%) cases.

Of the lesions found in the pancreas, the head was mainly involved, with 7 (58%) lesions.

Conclusions

EUS is an excellent tool for the screening and diagnosis of GEP-NET, as it provides a clear morphology of the lesions, an exact location, especially in tumours smaller than 2 cm. and has the possibility of aspiration biopsy for cytology diagnosis.