Rendimiento diagnóstico de repetir la biopsia guiada por ultrasonido endoscópico después de una primera biopsia negativa en pacientes con lesiones no pancreáticas

Endoscopia Pub Date : 2016-07-01 DOI:10.1016/j.endomx.2016.08.003

Félix I. Téllez-Ávila, Jorge Adolfo Martínez-Lozano, Gilberto Medrano-Duarte, Anamaría Rosales-Salinas, Francisco Valdovinos-Andraca, Ambrosio Rafael Bernal-Méndez, Camilo Guerrero-Velásquez, Miguel Ángel Ramírez-Luna

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Abstract

Introduction

Endoscopic ultrasound has been a useful method for the evaluation of pancreatobiliary pathology for more than a decade, however it is not unusual to find inconclusive pathological results in tissue obtained for diagnosis. The factors affecting diagnostic performance include; endosonographist experience, the volume of procedures performed, type, size and location, amongst others. The aim of this study was to evaluate the diagnostic performance of the second EUS-FNA in non-pancreatic lesions.

Material and methods

A retrospective cross-sectional study that includedpatients > 18 years who underwent EUS-FNA over a period of 8 years.

Results

150 procedures were performed in 132 patients with non-pancreatic lesions. Finally, the diagnosis was obtained by EUS-FNA in 114/132 patients for a diagnostic yield of 86.6%. In total, the biopsy median (minimum/maximum interval) was 1 (1-5). The diagnostic yield of the first EUS-FNA was 77.3% (102/132). With the second EUS-FNA 11/16 patients had a histological diagnosis (11/16 = 68.7%; global 85.6%). No complications were reported.

Conclusion

Repeat EUS-FNA in patients with non-pancreatic lesions is necessary in patients with a first negative EUS-FNA because it improves the diagnostic yield.

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非胰腺损伤患者首次活检阴性后内镜超声引导重复活检的诊断性能

引言十多年来，内窥镜超声一直是评估胰胆管病理的有用方法，但在诊断组织中发现不确定的病理结果并不罕见。影响诊断性能的因素包括：；内窥镜检查的经验、所进行的手术量、类型、大小和位置等。本研究的目的是评估第二次EUS-FNA对非胰腺病变的诊断性能。材料和方法一项包括患者>；18岁，在8年的时间里接受了EUS-FNA。结果132例非胰腺病变患者共行150例手术。最后，通过EUS-FNA对114/132名患者进行了诊断，诊断率为86.6%。总的来说，活检中位数（最小/最大间隔）为1（1-5）。首次EUS-FNA的诊断率为77.3%（102/132）。在第二次EUS-FNA中，11/16名患者得到了组织学诊断（11/16=68.7%；总体85.6%）。没有并发症报告。结论在首次EUS-FNA阴性的非胰腺病变患者中重复EUS-FNA是必要的，因为它可以提高诊断率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Endoscopia

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