J.-L. Lefebvre (Professeur) , D. Chevalier (Professeur)
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引用次数: 4
下咽癌症
尽管在外科、放射治疗、化疗和现代成像方面取得了重大进展,但下咽癌的预后仍然非常差。这些癌症最常发生在有长期吸烟和酗酒史的患者身上,在一半的病例中产生了显著的合并症,危及癌症重型疗法的实施。在超过四分之三的病例中,下咽癌被诊断为晚期。如果罕见的早期疾病可以通过放射治疗或手术治疗,晚期疾病需要进行根治性手术和术后放疗。然而,在早期疾病中5年生存率不超过50%,在接受治疗的晚期病例中5年存活率不超过35%。在接受姑息治疗的患者中,2年生存率不超过10%。在过去的二十年里,唯一真正的进步是在选定的病例中采用了保喉策略,在一半的病例中避免了切除喉部,但对生存没有任何影响。目前的研究重点是新的放射治疗方式、同时进行的化学-放射治疗方案和生物修复药物。
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