Biliary stent placement without endoscopic sphincterotomy in patients with common bile duct stones

GastroHep Pub Date : 2021-08-09 DOI:10.1002/ygh2.487
Aye-Mya-Mya Kyaw, Than-Than Aye, Khin-San Aye, Wai-Phyo Aung, Thet-Mar Win
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Abstract

Background

To avoid the late complications of endoscopic sphincterotomy (EST) such as cholangitis, liver abscess and recurrent common bile duct stones (CBDS), alternative methods should be considered in the management of CBDS, especially in younger patients.

Aim

To study the effect of biliary stent placement without EST in patients with CBDS.

Methods

Forty-nine patients with CBDS underwent biliary stent placement without EST and complications were evaluated. The rate of stone disappearance, the change in number, size and indices of stones and common bile duct (CBD) diameter were evaluated at the second endoscopic retrograde cholangiopancreatography (ERCP) 3 months later.

Results

CBDS(s) disappeared in 11 (22.45%) of 49 patients. Almost all of the stones which disappeared after stenting without EST were <14 mm and CBD diameter <18 mm. Average diameter of the largest CBDS, mean number of CBDS, stone index and CBD diameter markedly reduced (P < 0.001, P < 0.001, P < 0.001 and P = 0.001 respectively). The size of the largest stone, stone indices and diameter of CBD in the stone disappearance cases were significantly smaller than those of the stone persistence cases (P = 0.003, P = 0.006, P = 0.004 respectively). Complications such as mild post-ERCP pancreatitis (6.12%), stent migration (10.2%) and cholangitis (4.08%) were observed.

Conclusion

Temporary stent placement without EST is effective for clearance of CBDS while preserving the duodenal papilla function, especially in small CBDS and less dilated CBD to avoid EST related complications.

Abstract Image

未经内镜乳头括约肌切开术的胆道支架置入治疗胆总管结石
背景为了避免内镜乳头括约肌切开术(EST)的晚期并发症,如胆管炎、肝脓肿和复发性胆总管结石(CBDS),应考虑其他方法来治疗CBDS,尤其是在年轻患者中。目的探讨无EST胆道支架置入术治疗CBDS的疗效。方法对49例无EST的CBDS患者行胆道支架置入术,并对并发症进行评价。3个月后,在第二次内镜逆行胰胆管造影(ERCP)中评估结石消失率、结石数量、大小和指标的变化以及胆总管(CBD)直径。结果49例患者中CBDS消失11例(22.45%)。几乎所有在没有EST的情况下支架置入后消失的结石都<;14mm和CBD直径<;18毫米。最大CBDS的平均直径、平均CBDS数量、结石指数和CBD直径显著降低(分别为P<;0.001、P<;0.001P和P=0.001)。结石消失病例的最大结石大小、结石指数和CBD直径显著小于结石持续病例(分别为P=0.003、P=0.006、P=0.004)。并发症如ERCP术后轻度胰腺炎(6.12%)、支架移位(10.2%)和胆管炎(4.08%)。结论无EST的临时支架置入可有效清除CBDS,同时保留十二指肠乳头功能,尤其是在小CBDS和扩张较少的CBD中,可避免EST相关并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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