Resección conservadora del fibroelastoma papilar: resultados y revisión de la literatura

IF 0.3 Q4 SURGERY
Audelio Guevara-Bonilla, Pasquale Maiorano, Laura Castillo-Pardo, Gregorio Laguna-Núñez, Elio Martín-Gutiérrez, Javier Gualis-Cardona, María J. Alonso-Porto, Mario Castaño-Ruiz
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Abstract

Introduction and objectives

Papillary fibroelastoma is a benign primary cardiac tumor normally located in the valvular endocardium, although it can be found in other endocardial structures. According to recent studies, it could be the most common benign primary cardiac tumor. In a significant number of cases it is asymptomatic, diagnosed incidentally and, in symptomatic cases, usually they present as thromboembolic neurological events. We show our experience in the surgical treatment of papillary fibroelastoma and a review of the literature is performed.

Methods

Single-center retrospective study by reviewing the medical records of all patients diagnosed with papillary fibroelastoma and surgically treated in our department.

Results

From January 2016 to October 2022, 14 patients were operated on, predominantly men, with a mean age of 61 ± 12.6 years. The diagnosis was made mostly in almost all cases during the preoperative study for other indications. Most of the tumors were asymptomatic and were located in the aortic valve. No patient required valve replacement or repair. In 5 cases (35.7%) concomitant cryoablation was performed. There was no surgical mortality. After 3.2 ± 2.22 years of follow-up, two patients died of non-cardiac causes. No tumoral recurrences have been found.

Conclusions

Surgical treatment of papillary fibroelastoma is safe and offers good short and mid-term results. Concomitant cryoablation might be useful to achieve complete tumor removal without the need for valve replacement, however more evidence is mandatory. The realization of a multicenter registry would allow a better knowledge of this tumors.

保守切除乳头状纤维弹性瘤:结果及文献综述
引言和目的乳头弹性纤维瘤是一种良性原发性心脏肿瘤,通常位于心瓣膜,但也可在其他心内膜结构中发现。根据最近的研究,它可能是最常见的良性原发性心脏肿瘤。在相当多的病例中,它是无症状的,是偶然诊断的,在有症状的病例中通常表现为血栓栓塞性神经事件。我们展示了我们在乳头状弹性纤维瘤手术治疗方面的经验,并对文献进行了回顾。方法回顾性分析我科所有诊断为乳头状弹性纤维瘤并经手术治疗的患者的病历资料。结果从2016年1月到2022年10月,共有14名患者接受了手术,主要是男性,平均年龄为61±12.6岁。在其他适应症的术前研究中,几乎所有病例都做出了诊断。大多数肿瘤无症状,位于主动脉瓣。没有患者需要更换或修复瓣膜。5例(35.7%)同时行冷冻消融。没有手术死亡。经过3.2±2.22年的随访,两名患者死于非心脏原因。未发现肿瘤复发。结论乳头状弹性纤维瘤的手术治疗是安全的,具有良好的中短期疗效。伴随冷冻消融可能有助于在不需要瓣膜置换的情况下实现完全的肿瘤切除,但更多的证据是强制性的。多中心注册的实现将使人们更好地了解这种肿瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.50
自引率
66.70%
发文量
109
审稿时长
69 days
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