Vasomotion heterogeneity and spectral characteristics in diabetic and hypertensive patients

IF 2.9 4区医学 Q2 PERIPHERAL VASCULAR DISEASE

Microvascular research Pub Date : 2023-11-03 DOI:10.1016/j.mvr.2023.104620

Liangjing Zhao, Shuhong Liu, Yang Liu, Hui Tang

{"title":"Vasomotion heterogeneity and spectral characteristics in diabetic and hypertensive patients","authors":"Liangjing Zhao, Shuhong Liu, Yang Liu, Hui Tang","doi":"10.1016/j.mvr.2023.104620","DOIUrl":null,"url":null,"abstract":"<div>Vasomotion refers to the spontaneous oscillation of blood vessels within a frequency range of 0.01 to 1.6 Hz. Various disease states, including hypertension and diabetes, have been associated with alterations in vasomotion at the finger, indicating potential impairment of skin microcirculation. Due to the non-linear nature of human vasculature, the modification of vasomotion may vary across different locations for different diseases. In this study, Laser Doppler Flowmetry was used to measure blood flow motion at acupoints LU8, LU5, SP6, and PC3 among 49 participants with or without diabetes and/or hypertension. Fast Fourier Transformation was used to analyze noise type while Hilbert-Huang Transformation and wavelet analysis were applied to assess Signal Noise Ratio (SNR) results. Statistical analysis revealed that different acupoints exhibit distinct spectral characteristics of vasomotion not only among healthy individuals but also among patients with diabetes and/or hypertension. The results showed strong heterogeneity of vasomotion among blood vessels, indicating that the vasomotion measured at a certain point may not reflect the real status of microcirculation.</div>","PeriodicalId":18534,"journal":{"name":"Microvascular research","volume":"151 ","pages":"Article 104620"},"PeriodicalIF":2.9000,"publicationDate":"2023-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microvascular research","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0026286223001462","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PERIPHERAL VASCULAR DISEASE","Score":null,"Total":0}

引用次数: 0

Abstract

Vasomotion refers to the spontaneous oscillation of blood vessels within a frequency range of 0.01 to 1.6 Hz. Various disease states, including hypertension and diabetes, have been associated with alterations in vasomotion at the finger, indicating potential impairment of skin microcirculation. Due to the non-linear nature of human vasculature, the modification of vasomotion may vary across different locations for different diseases. In this study, Laser Doppler Flowmetry was used to measure blood flow motion at acupoints LU8, LU5, SP6, and PC3 among 49 participants with or without diabetes and/or hypertension. Fast Fourier Transformation was used to analyze noise type while Hilbert-Huang Transformation and wavelet analysis were applied to assess Signal Noise Ratio (SNR) results. Statistical analysis revealed that different acupoints exhibit distinct spectral characteristics of vasomotion not only among healthy individuals but also among patients with diabetes and/or hypertension. The results showed strong heterogeneity of vasomotion among blood vessels, indicating that the vasomotion measured at a certain point may not reflect the real status of microcirculation.

查看原文本刊更多论文

糖尿病和高血压患者的血管运动异质性和频谱特征。

血管运动是指血管在0.01至1.6的频率范围内自发振荡 赫兹。包括高血压和糖尿病在内的各种疾病状态都与手指血管运动的改变有关，这表明皮肤微循环可能受损。由于人类血管系统的非线性性质，血管运动的改变可能因不同疾病的不同位置而异。在本研究中，使用激光多普勒流量计测量49名患有或不患有糖尿病和/或高血压的参与者的LU8、LU5、SP6和PC3穴位的血流运动。快速傅立叶变换用于分析噪声类型，希尔伯特-黄变换和小波分析用于评估信噪比（SNR）结果。统计分析表明，不同穴位不仅在健康人中，而且在糖尿病和高血压患者中都表现出不同的血管运动频谱特征。结果显示，血管之间的血管运动具有很强的异质性，表明在某一点测量的血管运动可能不能反映微循环的真实状态。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Microvascular research 医学-外周血管病

CiteScore

6.00

自引率

3.20%

发文量

158

审稿时长

43 days

期刊介绍： Microvascular Research is dedicated to the dissemination of fundamental information related to the microvascular field. Full-length articles presenting the results of original research and brief communications are featured. Research Areas include: • Angiogenesis • Biochemistry • Bioengineering • Biomathematics • Biophysics • Cancer • Circulatory homeostasis • Comparative physiology • Drug delivery • Neuropharmacology • Microvascular pathology • Rheology • Tissue Engineering.