CLEFT LIP, ALVEOLUS AND PALATE IN AFRICAN NATIVES: AN UPDATE ON DEMOGRAPHICS AND MANAGEMENT OUTCOME.

O B Akintububo, E O Ojo, D D Kokong, S A Adamu, U U Nnadozie, Z Yunusa-Kaltungo, I Jalo, A M Dauda
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Abstract

Background: Development of craniofacial structures is a complex process and disruption of any of the numerous steps can lead to development of oro-facial clefts. This is a surgically amenable anomaly as from early life that has had conflicting pattern of demographics reported by various researchers globally. There are several factors that are critical to the surgical outcome.

Objective: Study the demographics and the management outcome of cleft lip, alveolus and palate and highlight factors responsible for improved care in recent time.

Design: Descriptive cohort study.

Setting: Tertiary health institution.

Method: All consecutive patients managed for cleft lip, alveolus and palate (CLAP) over 7years and 10months were studied.

Outcome: Cleft lip, alveolus and palate repair was performed on 149 patients, January 1, 2001- December 31, 2008 with an incidence of 2.1/1000 live births. From this, 27 patients, averaging 4.5 patients per year were operated for the first 6 1/3 years while the remaining 122(81.9%) the next 1 1/2 years, averaging 81.6 patients yearly. Their ages ranged from 3 months - 60 years with 77 (51.7%) males and 72 (48.3.0%) females. Cleft lip was the main presentation in 108(72.5%) of which 72(66.7%) were left sided. Bilateral cleft lip were14 (9.4%). Five (3.4%) patients had associated anomalies out of which 3(60.0%) had CLAP while 2(40.0%) isolated cleft lip or palate. The technique for cleft lip repair was Millard's and Noordhoof's while palatal cleft was the two-flap palatoplasty with intravelar veloplasty. Success was recorded in 142(95.3%) with complication observed in 7(4.7%) patients.

Conclusion: The rarity of cleft lip, alveolus and/or palate in the African native documented previously may no longer be tenable as observe in this study. Management outcome has improved owing to the collaboration with SmileTrain, USA, along with multidisciplinary approach.

非洲原住民的唇、牙槽和腭裂:人口统计和管理结果的更新。
背景:颅面结构的发育是一个复杂的过程,任何一个步骤的破坏都可能导致颅面裂的发展。这是一种可手术治疗的异常现象,来自早期,全球各研究人员报告的人口统计模式相互矛盾。有几个因素对手术结果至关重要。目的:研究唇腭裂的人口统计学和治疗结果,并强调近年来改善护理的因素。设计:描述性队列研究。设置:三级卫生机构。方法:对连续7年零10个月的唇腭裂患者进行研究。结果:2001年1月1日至2008年12月31日,对149名患者进行了唇腭裂、肺泡腭裂修复,发生率为2.1/1000活产。其中,27名患者(平均每年4.5名患者)在前6年半接受了手术,其余122名患者(81.9%)在接下来的1年半接受手术,平均每年81.6名患者。年龄在3个月至60岁之间,其中男性77人(51.7%),女性72人(48.3.0%)。唇腭裂108例(72.5%),其中左侧72例(66.7%)。双侧唇裂14例(9.4%),5例(3.4%)有相关异常,其中3例(60.0%)有CLAP,2例(40.0%)为孤立性唇腭裂。唇裂修复术采用Millard和Noordhove两种方法,腭裂修复术采用两瓣腭部成形术和腔内发育成形术。142例(95.3%)患者成功,7例(4.7%)患者出现并发症。结论:正如本研究所观察到的,先前记录的非洲原住民罕见的唇、牙槽和/或腭裂可能不再成立。由于与美国SmileTrain的合作以及多学科方法,管理成果有所改善。
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