Protection of Lotus Seedpod Proanthocyanidins on Organs and Tissues under High-intensity Excercise.

Q3 Medicine
Open Biomedical Engineering Journal Pub Date : 2015-10-13 eCollection Date: 2015-01-01 DOI:10.2174/1874120701509010296
Zhang Mengyan
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引用次数: 3

Abstract

Lotus seedpod proanthocyanidins (LSPC) as a kind of polyphenols is widely used in medicines, cosmetics, health products. High-intensity exercise can cause damage to the body's organs and tissues. Different doses of LSPC is given to mice to check the function of protect effect to the body's organs and tissues under high-intensity exercise. The hemoglobin (HB) content, red blood cell (RBC) number and white blood cell (WBC) number were tested for mice after exercise. The activity of superoxide dismutase (SOD) and the contents of glutathione (GSH) and malondialdehyde (MDA) in muscle and viscera were evaluated. The result showed that LSPC can effectively reduce inflammation reaction in the body of mice with high intensity exercise, alleviate oxidative stress-induced injury of tissues and organs, and execute protective function on skeletal muscle and cardiac muscle. And the LSPC could enhance myocardial anti-oxygen and enzymatic activity which suggests the protective effects of resveratrol against exercise-induced myocardial damage in mice.

Abstract Image

Abstract Image

Abstract Image

莲藕原花青素对高强度运动器官组织的保护作用。
莲蓬原花青素(LSPC)作为一种多酚类物质,广泛应用于医药、化妆品、保健品中。高强度运动会对身体的器官和组织造成损伤。给小鼠服用不同剂量的LSPC,观察高强度运动对机体器官和组织的保护作用。运动后测定小鼠血红蛋白(HB)含量、红细胞(RBC)数和白细胞(WBC)数。测定肌肉和内脏超氧化物歧化酶(SOD)活性、谷胱甘肽(GSH)和丙二醛(MDA)含量。结果表明,LSPC能有效降低高强度运动小鼠体内的炎症反应,减轻氧化应激对组织器官的损伤,对骨骼肌和心肌具有保护作用。LSPC能增强心肌抗氧化和酶活性,提示白藜芦醇对运动性心肌损伤的保护作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Open Biomedical Engineering Journal
Open Biomedical Engineering Journal Medicine-Medicine (miscellaneous)
CiteScore
1.60
自引率
0.00%
发文量
4
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