Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria.

Q3 Medicine
Ngozika E Ezinne, Michael A Kwarteng, Kingsley K Ekemiri, Victoria I Iroanachi, Selassie Tagoh, Grace Ogbonna, Khathutshelo P Mashige
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Abstract

Aim: Globally, one of the leading causes of preventable blindness is primary open-angle glaucoma (POAG). The study assessed the clinical presentations of POAG patients attending an eye center in Abuja, Nigeria.

Materials and methods: Records of 188 eyes, collected from 94 patients diagnosed with POAG for a period of 1 year at the eye center, were reviewed. Clinical records, including age, gender, visual acuity (VA), central cornea thickness (CCT), intraocular pressure (IOP), cup-to-disk ratios, and retinal nerve fiber layer (RNFL) thickness of the participants, were extracted and analyzed.

Results: The majority of the participants were males (56.4%) and adults (57.4%), most of whom had normal VA (>70% in each eye). Our analysis revealed normal average estimates of RNFL thickness, IOP, and CCT among the participants. Females had thicker RNFL compared to males (p = 0.02). Although CCT decreased with age (r = -0.28, p = 0.005), there was no such link between IOP and CCT (r = 0.09, p = 0.38).

Conclusion: Central cornea thickness (CCT), RNFL thickness, and IOP in isolation should not be used as early indicators for POAG; rather, a combination of these and other indices is recommended. Early detection through active screening and treatment in the community for at-risk groups is highly advised.

How to cite this article: Ezinne NE, Kwarteng MA, Ekemiri KK, et al. Clinical Profile of Primary Open-angle Glaucoma Patients at an Eye Center in Nigeria. J Curr Glaucoma Pract 2023;17(3):113-117.

尼日利亚眼科中心原发性开角型青光眼患者的临床资料。
目的:在全球范围内,原发性开角型青光眼是可预防失明的主要原因之一。该研究评估了在尼日利亚阿布贾一家眼科中心就诊的POAG患者的临床表现。材料和方法:回顾了在该眼科中心就诊1年的94名POAG患者中收集的188只眼睛的记录。提取并分析参与者的临床记录,包括年龄、性别、视力(VA)、中央角膜厚度(CCT)、眼压(IOP)、杯盘比和视网膜神经纤维层(RNFL)厚度。结果:大多数参与者是男性(56.4%)和成年人(57.4%),其中大多数人的VA正常(每只眼睛>70%)。我们的分析显示,参与者的RNFL厚度、IOP和CCT的平均估计值正常。与男性相比,女性的RNFL较厚(p=0.02)。尽管CCT随着年龄的增长而降低(r=-0.28,p=0.005),但IOP和CCT之间没有这种联系(r=0.09,p=0.038)。结论:中央角膜厚度(CCT)、RNFL厚度和单独的IOP不应作为POAG的早期指标;相反,建议将这些指数与其他指数相结合。强烈建议在社区中通过积极筛查和治疗对高危人群进行早期发现。如何引用这篇文章:Ezinne NE,Kwarteng MA,Ekmemiri KK等。尼日利亚眼科中心原发性开角型青光眼患者的临床概况。青光眼临床杂志2023;17(3):113-117。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Current Glaucoma Practice
Journal of Current Glaucoma Practice Medicine-Ophthalmology
CiteScore
1.00
自引率
0.00%
发文量
38
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