Clinical Value of Clip-and-Snare Assisted Endoscopic Submucosal Resection in Treatment of Rectal Neuroendocrine Tumors.

IF 1.8 4区医学 Q3 GASTROENTEROLOGY & HEPATOLOGY

Visceral Medicine Pub Date : 2023-10-01 Epub Date: 2023-09-05 DOI:10.1159/000533393

Xin-Tong Jiang, Yang Hu, Jian Gong, Shi-Bin Guo

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引用次数: 0

Abstract

Introduction: The aim of the study was to introduce a new endoscopic technology, clip-and-snare assisted endoscopic submucosal resection (CS-ESMR), for treatment of rectal neuroendocrine tumors (NETs) and then to investigate the therapeutic value of CS-ESMR.

Methods: In this retrospective study, 67 patients who underwent endoscopic treatment of rectal NETs from March 2017 to December 2021 were analyzed. According to the endoscopic resection methods (endoscopic mucosal resection [EMR], CS-ESMR, and endoscopic submucosal dissection [ESD]), the cases were divided into CS-ESMR group (27 cases), ESD group (31 cases), and EMR group (9 cases). The pathological R0 resection rate and the incidence of adverse events (bleeding and perforation) were compared among the three groups.

Results: There was a significant difference about the pathological R0 resection between the CS-ESMR group and the EMR group and between the CS-ESMR group and the ESD group (both p < 0.05). Compared with ESD group, the procedure time, intraoperative bleeding, and the cost of CS-ESMR group are significantly decreased (p < 0.001, p < 0.05, p < 0.001, respectively).

Conclusion: CS-ESMR may be a safe and effective treatment for rectal NETs with a diameter of less than 10 mm, without muscularis propria invasion and metastasis.

查看原文本刊更多论文

钳夹和圈套辅助内镜下黏膜下切除术治疗直肠神经内分泌肿瘤的临床价值。

引言：本研究的目的是介绍一种新的内镜技术，即夹套辅助内镜黏膜下切除术（CS-ESMR），用于治疗直肠神经内分泌肿瘤（NETs），然后探讨CS-ESMR的治疗价值。方法：在本回顾性研究中，对2017年3月至2021年12月接受直肠NETs内镜治疗的67名患者进行了分析。根据内镜切除方法（内镜黏膜切除[ERR]、CS-ESMR和内镜黏膜下剥离[ESD]），将病例分为CS-ESMR组（27例）、ESD组（31例）和EMR组（9例）。比较三组的病理R0切除率和不良事件（出血和穿孔）的发生率。结果：CS-ESMR组与EMR组及CS-ESMR与ESD组在病理性R0切除方面有显著性差异（均p<0.05），结论：CS-ESMR治疗直径小于10mm、无固有肌层浸润和转移的直肠NETs是一种安全有效的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Visceral Medicine Medicine-Surgery

CiteScore

4.50

自引率

0.00%

发文量

期刊介绍： This interdisciplinary journal is unique in its field as it covers the principles of both gastrointestinal medicine and surgery required for treating abdominal diseases. In each issue invited reviews provide a comprehensive overview of one selected topic. Thus, a sound background of the state of the art in clinical practice and research is provided. A panel of specialists in gastroenterology, surgery, radiology, and pathology discusses different approaches to diagnosis and treatment of the topic covered in the respective issue. Original articles, case reports, and commentaries make for further interesting reading.