Frequency and Characteristics of Spinal Bleeding Sources in Nontraumatic Angiogram-Negative Subarachnoid Hemorrhage.

IF 2 Q3 PERIPHERAL VASCULAR DISEASE

Cerebrovascular Diseases Extra Pub Date : 2023-01-01 Epub Date: 2023-10-28 DOI:10.1159/000534529

Tim Lampmann, Simon Brandecker, Johannes Weller, Frederic Carsten Schmeel, Harun Asoglu, Motaz Hamed, Alexander Radbruch, Erdem Güresir, Hartmut Vatter, Mohammed Banat

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引用次数: 0

Abstract

Introduction: Angiogram-negative subarachnoid hemorrhage (AN-SAH) accounts for 5-15% of spontaneous SAH. This study aims to analyze the frequency and characteristics of spinal bleeding sources in patients with AN-SAH.

Methods: 140 patients suffering from AN-SAH treated at our institution from 2012 to 2022 were included in this retrospective cohort study.

Results: 52.1% were diagnosed with perimesencephalic SAH, 35.0% with non-perimesencephalic, SAH and 12.9% with CT-negative SAH (diagnosed by lumbar puncture). Additional magnetic resonance imaging (MRI) identified a spinal bleeding source in 4 patients (2.86%). These patients presented with local spine pain or neurological deficits (relative risk: 3.9706 [95% confidence interval [CI]: 0.7272-21.6792]; p < 0.001) and were younger (mean difference 14.85 years [95% CI: 0.85-28.85; p = 0.038]) compared to patients without a spinal bleeding source.

Conclusions: AN-SAH caused by spinal pathology is rare. This study indicates that craniocervical and holospinal MRI should be considered in AN-SAH, especially for young patients with AN-SAH who present with back pain or neurological deficits.

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非创伤性血管造影阴性蛛网膜下腔出血中脊髓出血源的频率和特征。

简介：血管造影阴性蛛网膜下腔出血（AN-SAH）占自发性SAH的5-15%。本研究旨在分析AN-SAH患者脊柱出血源的频率和特征。方法：本回顾性队列研究纳入了2012年至2022年在我院接受治疗的140名AN-SAH患者。结果：52.1%诊断为中脑周围性蛛网膜下腔出血，35.0%诊断为非中脑周围性SAH，12.9%诊断为CT阴性SAH（经腰椎穿刺诊断）。额外的MRI发现4名患者（2.86%）的脊椎出血源。这些患者表现为局部脊椎疼痛或神经功能缺损（RR 3.9706[95%-CI:0.7272-21.6792]；结论：由脊柱病理引起的AN-SAH是罕见的。这项研究表明，在AN-SAH中应考虑进行颅颈和全脊髓MRI检查，尤其是对于伴有背痛或神经功能缺损的年轻AN-SAH患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cerebrovascular Diseases Extra PERIPHERAL VASCULAR DISEASE-

CiteScore

3.50

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： This open access and online-only journal publishes original articles covering the entire spectrum of stroke and cerebrovascular research, drawing from a variety of specialties such as neurology, internal medicine, surgery, radiology, epidemiology, cardiology, hematology, psychology and rehabilitation. Offering an international forum, it meets the growing need for sophisticated, up-to-date scientific information on clinical data, diagnostic testing, and therapeutic issues. The journal publishes original contributions, reviews of selected topics as well as clinical investigative studies. All aspects related to clinical advances are considered, while purely experimental work appears only if directly relevant to clinical issues. Cerebrovascular Diseases Extra provides additional contents based on reviewed and accepted submissions to the main journal Cerebrovascular Diseases.