Desmoid fibroma simulating malignant breast neoplasm: A case report and literature review.

Breast disease Pub Date : 2023-01-01 DOI:10.3233/BD-230028
Maria Stella Vasconcelos Sales Valente, Fábio Augusto Xerez Mota, Bárbara Bezerra Ricciardi, Bárbara Matos de Carvalho Borges, Enzo Studart de Lucena Feitosa, Pedro Lucena de Aquino, Paulla Vasconcelos Valente
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引用次数: 0

Abstract

Introduction: Desmoid fibroma (DF) is a disorder characterized by strong clonal proliferation of myofibroblasts and fibroblasts. We describe a case of DF that mimicked a breast tumor, along with a review of the literature on the clinical manifestation, diagnostic process, and course of therapy for this combative disease.

Case report: A 34-year-old female patient with breast lump at the junction of the upper quadrants of the left breast. After the diagnosis of DF, it was decided to perform a sectorectomy of the left breast associated with post-quadrant reconstruction, with immunohistochemistry and findings compatible with DF.

Discussion: Clinically manifests as a solid mass that is often painless and occasionally adherent to the chest wall. A treatment strategy should be idealized for each patient. Thus, there is the possibility of performing radical surgery for resection and/or radiotherapy, and surgery may be followed by radiotherapy.

模拟乳腺恶性肿瘤的筛状纤维瘤:一例报告和文献复习。
引言:筛状纤维瘤(DF)是一种以肌成纤维细胞和成纤维细胞的强烈克隆性增殖为特征的疾病。我们描述了一个模仿乳腺肿瘤的DF病例,并回顾了关于这种对抗性疾病的临床表现、诊断过程和治疗过程的文献。病例报告:一名34岁女性患者,左乳房上象限交界处有乳房肿块。在诊断出DF后,决定进行左乳腺切除术,并进行象限后重建,免疫组织化学和结果与DF一致。讨论:临床表现为固体肿块,通常无痛,偶尔粘附在胸壁上。每个病人的治疗策略都应该是理想化的。因此,有可能进行根治性手术进行切除和/或放射治疗,手术后可能进行放射治疗。
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来源期刊
Breast disease
Breast disease Medicine-Oncology
CiteScore
1.80
自引率
0.00%
发文量
59
期刊介绍: The recent expansion of work in the field of breast cancer inevitably will hasten discoveries that will have impact on patient outcome. The breadth of this research that spans basic science, clinical medicine, epidemiology, and public policy poses difficulties for investigators. Not only is it necessary to be facile in comprehending ideas from many disciplines, but also important to understand the public implications of these discoveries. Breast Disease publishes review issues devoted to an in-depth analysis of the scientific and public implications of recent research on a specific problem in breast cancer. Thus, the reviews will not only discuss recent discoveries but will also reflect on their impact in breast cancer research or clinical management.
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