Stochastic model of drug concentration level during IV-administration

IF 1 Q1 MATHEMATICS
I. Dzhalladova, Miroslava R��i�kov�
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Abstract

A stochastic model describing the concentration of the drug in the body during its IV-administration is discussed. The paper compares a deterministic model created with certain simplifications with the stochastic model. Fluctuating and irregular patterns of plasma concentrations of some drugs observed during intravenous infusion are explained. An illustrative example is given with certain values of drug infusion rate and drug elimination rate.
静脉给药期间药物浓度水平的随机模型
本文讨论了一种描述药物在静脉给药期间体内浓度的随机模型。本文将经过一定简化建立的确定性模型与随机模型进行了比较。在静脉输注期间观察到的一些药物的血药浓度的波动和不规则模式被解释。给出了一个具有一定输注速率和药物消除速率值的说明性实例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Opuscula Mathematica
Opuscula Mathematica MATHEMATICS-
CiteScore
1.70
自引率
20.00%
发文量
30
审稿时长
22 weeks
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