Stem cells and the pancreas: from discovery to clinical approach

IF 0.3 Q4 PEDIATRICS

Journal of Pediatric and Neonatal Individualized Medicine Pub Date : 2016-02-29 DOI:10.7363/050130

A. Dessì, S. Marras, Giorgia Locci, A. D. Magistris, V. Fanos, G. Faa

引用次数: 1

Abstract

The existence of stem cells within the adult pancreas is supported by the ability of this organ to regenerate its endocrine component in various conditions such as pregnancy and following partial pancreatectomy. Several studies have shown that progenitor or adult stem cells may reside within the pancreas and particularly in the pancreatic ducts, including acinar cells and islets of Langerhans. The discovery of human pluripotent stem cells in the pancreas, and the possibility of development of strategies for generating these, represented a turning point for the therapeutic interventions of type 1 diabetes.Proceedings of the 2nd International Course on Perinatal Pathology (part of the 11th International Workshop on Neonatology · October 26th-31st, 2015) · Cagliari (Italy) · October 31st, 2015 · Stem cells: present and future Guest Editors: Gavino Faa, Vassilios Fanos, Antonio Giordano

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干细胞和胰腺:从发现到临床方法

成人胰腺中干细胞的存在是由该器官在各种情况下(如怀孕和部分胰腺切除术后)再生其内分泌成分的能力所支持的。几项研究表明，祖细胞或成体干细胞可能存在于胰腺内，特别是胰管中，包括腺泡细胞和朗格汉斯岛。胰腺中人类多能干细胞的发现，以及产生这些干细胞的策略发展的可能性，代表了1型糖尿病治疗干预的一个转折点。第二届围产期病理学国际课程论文集(第11届新生儿国际研讨会的一部分)·卡利亚里(意大利)·2015年10月31日·干细胞:现在和未来客座编辑:Gavino Faa, Vassilios Fanos, Antonio Giordano

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来源期刊

Journal of Pediatric and Neonatal Individualized Medicine PEDIATRICS-

CiteScore

1.00

自引率

25.00%

发文量

审稿时长

12 weeks

期刊介绍： The Journal of Pediatric and Neonatal Individualized Medicine (JPNIM) is a peer-reviewed interdisciplinary journal which provides a forum on new perspectives in pediatric and neonatal medicine. The aim is to discuss and to bring readers up to date on the latest in research and clinical pediatrics and neonatology. Special emphasis is on developmental origin of health and disease or perinatal programming and on the so-called ‘-omic’ sciences. Systems medicine blazes a revolutionary trail from reductionist to holistic medicine, from descriptive medicine to predictive medicine, from an epidemiological perspective to a personalized approach. The journal will be relevance to clinicians and researchers concerned with personalized care for the newborn and child. Also medical humanities will be considered in a tailored way. Article submission (original research, review papers, invited editorials and clinical cases) will be considered in the following fields: fetal medicine, perinatology, neonatology, pediatrics, developmental programming, psychology and medical humanities.