Metastatic Sebaceous Carcinoma Presenting as Cheek Nodule: A Rare Case

Abstract

Sebaceous Carcinoma is a rare locally aggressive tumour of adnexal epithelium with a potential to metastasize to regional lymph node and distant organs. It constitutes between 1.5 to 5% of all eyelid malignant tumours. After basal cell and squamous cell carcinomas, it ranks third in incidence. Sebaceous carcinoma is seen more commonly in elderly females with average age at diagnosis in mid-sixties. Few cases have been reported in paediatric age group. Sebaceous Gland Carcinoma (SGC) is a slowly progressive tumor that arises usually from the meibomian gland in the eyelid, and has a locally aggressive nature with a tendency for pagetoid spread. The neoplasm is known to masquerade other benign and less malignant lesions. The non-specific clinical symptoms may lead to a delay in diagnosis of sebaceous carcinoma of the eyelid. Less than 120 cases of extra-occular sebaceous cell carcinoma have been reported so far. Here, the authors present a case of 60 years old female patient, who presented with cheek nodule and cytological diagnosis of metastatic sebaceous carcinoma was made based on cytomorphological features.