“Sandwich Technique” via a Right Ventricular Incision for Ultra-acute Repair of Post-infarction Ventricular Septal Defects

S. Isoda, R. Izubuchi, I. Yamazaki, K. Uchida, Shotaro Kaneko, M. Goda, Yoshimi Yano, M. Masuda
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Abstract

Post-infarction ventricular septal defect (VSD) is a life-threatening complication of transmural acute myocardial infarction (AMI), with a poor survival rate despite medical therapy 1, . Untreated patients had a 24% mortality rate in a day and 80% within the first month 3, . Although surgical repair seems to provide better result than medical therapy, surgical results in 2014 in Japan showed 28.6% 30-day mortality rate and 33.5% in-hospital mortality rate 5, . The Society of Thoracic Surgeons database showed operative mortality rate of 54.1% when repair was attempted within 7 days after AMI . Although untreated post-infarction VSD in the ultra-acute phase has an extremely high mortality rate, surgeons are reluctant to perform emergent surgery due to fragility of the infarcted myocardium. Problems with the previous surgical techniques include residual leak, uncontrolled bleeding, and technical difficulty 2, -. To resolve these problems, we have developed a sandwich technique via a right ventricular (RV) approach -. This technique involves the placement of patches on both the left and right sides of the septum, pinching the VSD sealed with surgical adhesive between the two patches via an RV approach (Fig. 1a). Since patients with post-infarction VSD tend to fall in severe lung edema or cardiac tamponade quickly and the condition sometimes become irreversible, necessitating postoperative cardiopulmonary support, we used our technique in the ultra-acute phase, with the Original Article
“三明治技术”经右心室切口超急性修复梗死后室间隔缺损
梗死后室间隔缺损(VSD)是跨壁急性心肌梗死(AMI)的一种危及生命的并发症,尽管药物治疗,但生存率很低。未经治疗的患者一天死亡率为24%,第一个月内死亡率为80%。虽然手术修复似乎比内科治疗提供更好的效果,但2014年日本手术结果显示,30天死亡率为28.6%,住院死亡率为33.5% 5,。胸外科学会数据库显示,AMI术后7天内尝试修复的手术死亡率为54.1%。尽管在超急性期未经治疗的梗死后室间隔缺损死亡率极高,但由于梗死心肌的脆弱性,外科医生不愿进行紧急手术。以前的手术技术存在的问题包括残留渗漏、无法控制的出血和技术难度2、-。为了解决这些问题,我们开发了一种通过右心室(RV)入路的夹层技术。该技术包括在鼻中隔的左右两侧放置贴片,通过RV入路夹住两个贴片之间用外科粘合剂密封的VSD(图1a)。由于梗死后VSD患者往往会迅速出现严重的肺水肿或心包填塞,有时病情变得不可逆转,需要术后心肺支持,因此我们在超急性期使用了我们的技术,并发表了原始文章
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