Laser treatment for stretch marks: a literature review

André C Nepomuceno, Larissa Cassemiro Da-Silva
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引用次数: 3

Abstract

Stretch marks are scars on the dermis that cause patients to be self-conscious and that pose challenges in clinical treatment. They result from rapid stretching of the skin and often observed in adolescents, pregnant women, obese individuals, and people experiencing rapid change in weight. They initially appear as erythematous and edematous plaques (red striae), and as they mature, they become whitish and atrophic (striae alba) due to the degradation and reorganization of elastin and collagen fibers. Currently, laser treatment is an emerging noninvasive therapeutic modality that is successful in reducing the excessive vascularization of red striae and in stimulating the production of collagen and elastin in the alba. In the present literature review, PubMed was searched for articles on the treatment of atrophic striations with laser that were published from January 2000 to December 2016. The authors have found 28 articles that met the inclusion criteria. Only few randomized clinical trials have evaluated the long-term efficacy and safety of energybased treatments. Based on clinical cases and systematic reviews, both ablative and non-ablative fractional lasers caused moderate improvement in the appearance of distending striae. The 1540-nm non-ablative fractional laser is more likely to be considered the first-line treatment for stretch marks. However, future studies should focus on research with longer duration, studies with objective and standardized measures for the evaluation of results, such as biopsy results, and molecular studies showing an increase in elastic and collagen fibers that correlate to the improvement in the clinical appearance of the striae after using lasers with systematized parameters. ■ ABSTRACT
激光治疗妊娠纹:文献综述
妊娠纹是真皮上的疤痕,会引起患者的自我意识,给临床治疗带来挑战。它们是由皮肤快速拉伸引起的,常见于青少年、孕妇、肥胖者和体重变化迅速的人群。它们最初表现为红斑和水肿斑块(红色条纹),随着它们的成熟,由于弹性蛋白和胶原纤维的降解和重组,它们变得苍白和萎缩(白色条纹)。目前,激光治疗是一种新兴的非侵入性治疗方式,它成功地减少了红纹的过度血管化,并刺激了白质中胶原蛋白和弹性蛋白的产生。在本文献综述中,检索PubMed检索2000年1月至2016年12月发表的关于激光治疗萎缩性条纹的文章。作者发现了28篇符合纳入标准的文章。只有少数随机临床试验评估了能量治疗的长期疗效和安全性。根据临床病例和系统回顾,烧蚀和非烧蚀分数激光对扩张纹的外观都有中等程度的改善。1540纳米非烧蚀分数激光更有可能被认为是妊娠纹的一线治疗方法。然而,未来的研究应侧重于更长时间的研究,具有客观和标准化的结果评估方法的研究,例如活检结果,以及显示弹性纤维和胶原纤维增加的分子研究,这些研究与使用系统化参数的激光后条纹临床外观的改善有关。■文摘
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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