Bidentate Lactate Binding to La(III)-Cu(II) Metallacrown with L-Phenylalaninehydroximate Ligands: the Chiral Separation of L-Lactate

Abstract

The chiral La(III)-Cu(II) metallacrown bearing L-phenylalaninehydroximate ligands was probed for complexation towards racemic lactate. X-Ray diffraction analysis revealed the bidentate chelation of L-lactate in the solid state to form enantiopure crystals. L-Phenylalaninehydroximate La(III)-Cu(II) metallacrown showed, therefore, a strong preference for coordination of the L-type lactate providing the chiral separation of the target compound.