Development and evaluation of an iOS vancomycin clinical decision support software application

Abstract

Background: Due to changes in treatment guidelines, traditional pharmacokinetic based dosing and existing vancomycin nomograms may not predict doses adequate for reaching the increased trough concentration goals. A novel nomogram was created to achieve the updated goals, and the nomogram was previously validated at our institution. For this study, the nomogram was converted into an iOS vancomycin clinical decision support software (CDSS) application.