Retrospective Evaluation of Term Neonatal Cases with Indirect Hyperbilirubinemia

Q4 Medicine
Rezzan Ezgi Ekin, S. Ertuğrul, I. Deger, İ. Yolbaş
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引用次数: 0

Abstract

Although jaundice is very common in the neonatal period, it often recovers spontaneously without the need for treatment. In this study, it was aimed to retrospectively evaluate the patients hospitalized with the diagnosis of hyperbilirubinemia and to determine the risk factors, thus, to early diagnose and guide treatment of severe hyperbilirubinemia. In this study, 250 infants who were followed up and treated for hyperbilirubinemia in Neonatal Intensive Care Unit. When all cases were evaluated etiologically, the highest reason was found to be AB0 incompatibility. In 30% of the cases, the direct Coombs test was positive and the most common reason in the cases with positive direct Coombs test was the association of Rh and subgroup incompatibility with a rate of 29.3%. When the treatments applied to the cases were evaluated, phototherapy was given to all patients. It was found that of the patients, 84% received only phototherapy treatment, 6.4% underwent exchange transfusion with phototherapy, 5.2% received IVIG treatment, 4.4% received exchange transfusion and IVIG treatment. If neonatal hyperbilirubinemia is not diagnosed and treated early, the morbidity and mortality of the brain damage that can occur is high. Today, while AB0 and Rh incompatibilities, which are an important etiologically important problem, are closely monitored, other etiological conditions such as infections, G6PD deficiency, subgroup incompatibility, hypothyroidism should also be kept in mind and early diagnosis and treatment should be performed.
间接性高胆红素血症足月新生儿的回顾性评价
虽然黄疸在新生儿时期很常见,但它往往不需要治疗就能自行恢复。本研究旨在回顾性评价诊断为高胆红素血症的住院患者,确定其危险因素,以便早期诊断和指导重度高胆红素血症的治疗。在这项研究中,250名高胆红素血症的婴儿在新生儿重症监护病房进行了随访和治疗。对所有病例进行病因学分析,发现AB0不相容是最主要的病因。在30%的病例中,直接库姆斯试验呈阳性,在直接库姆斯试验呈阳性的病例中,最常见的原因是Rh和亚组不相容的关联,占29.3%。当对所有病例的治疗方法进行评估后,对所有患者进行光疗。结果发现,仅接受光疗的患者占84%,接受光疗换血的患者占6.4%,接受IVIG治疗的患者占5.2%,接受换血和IVIG治疗的患者占4.4%。如果新生儿高胆红素血症没有得到早期诊断和治疗,可能发生的脑损伤的发病率和死亡率很高。今天,虽然AB0和Rh不相容是一个重要的病因学问题,密切监测,其他病因学情况,如感染,G6PD缺乏症,亚群不相容,甲状腺功能减退也应牢记,并应进行早期诊断和治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Eastern Journal of Medicine
Eastern Journal of Medicine Medicine-Medicine (all)
CiteScore
0.40
自引率
0.00%
发文量
61
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