SIGNIFICANCE OF PLATELET COUNT AND PLATELET INDICES IN PATIENTS WITH SOME THROMBOCYTOPENIC CONDITIONS

Omer Abdalla, T. Elsayed, H. Waggiallah
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引用次数: 1

Abstract

Background: Thrombocytopenia is one of the most frequent causes for hematologic consultation in the practice of medicine and can result from a wide variety of conditions. Objective: The study was conducted on behave of platelets count in tie with platelet volume indices to measure their consistency. Methods: The study was “prospective cross-sectional hospital based design” and conducted at Khartoum hospitals (A.Gasim, Jafar I A, and R.ICK). Studied populations texture has stipulated concurred diagnosis of heart disorders (HD), lymphoid neoplasms (LN), hypoplastic bone marrow (HPB), renal transplantation (RT), patients under chemotherapy (CT), and fully checked healthy Sudanese population (HSP). Platelet (PLT) count and platelet volume index (PVI) were measured using automated method of Sysmex KX-21N and the data was analyzed using SPSS. Results: does established (24) mean and standard for the study population among which (HSP) was platelet distribution width (PDW) (11.4±1.5 fl), mean platelet volume (MPV) (9.3±0.8 fl), platelet large cell ratio (PLCR) (20.6±6.7%) and PLT count (245±45 X109/L), and established correlations between PLT count and PVI in thrombocytopenic conditions. Conclusion: we conclude that, PVI has the ability to change from normal to higher or lower than (HSP) in thrombocytopenic conditions and Sudanese has PVI mean lower than the mean of reference range, and there are inverse and reverse correlations between PLT count and PVI but not in (HSP) and reverse correlation in between PVI except between PDW and P-LCR in (HPB)
血小板计数和血小板指数在某些血小板减少性疾病患者中的意义
背景:血小板减少症是医学实践中血液学会诊最常见的原因之一,可由多种情况引起。目的:研究血小板计数与血小板体积指标的关系,以衡量二者的一致性。方法:本研究采用“前瞻性横断面医院设计”,在喀土穆医院(A.Gasim, Jafar I A和r.k k)进行。研究人群的结构规定了心脏病(HD)、淋巴样肿瘤(LN)、骨髓发育不良(HPB)、肾移植(RT)、化疗患者(CT)和全面检查的健康苏丹人群(HSP)的并发诊断。采用Sysmex KX-21N自动方法测定血小板(PLT)计数和血小板体积指数(PVI),并用SPSS软件对数据进行分析。结果:建立了血小板分布宽度(PDW)(11.4±1.5 fl)、平均血小板体积(MPV)(9.3±0.8 fl)、血小板大细胞比(PLCR)(20.6±6.7%)、PLT计数(245±45 X109/L)为研究人群的平均值和标准(24),并建立了血小板减少条件下PLT计数与PVI的相关性。结论:血小板减少患者PVI具有从正常到高于或低于(HSP)的变化能力,苏丹患者PVI均值低于参考范围均值,PLT计数与PVI之间存在正相关和负相关关系,但在(HSP)中不存在;PVI与PVI之间存在负相关关系,但在(HPB)中PDW与P-LCR之间存在负相关关系。
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