Serum Zinc Levels in Patients with Acne Vulgaris and Its Correlation with Severity of Acne

Abstract

Objective: Acne vulgaris the most common cutaneous disorder affecting adolescent and young adults. Zinc is an essential element for human. We aimed to evaluate the serum zinc level in patients with acne vulgaris and correlate with the severity of disease. Methods: The study included 43 patients with acne vulgaris and 37 healthy control subjects. The severity of acne was assessed according to Global Acne Grading System. The serum zinc levels were measured both patients and control subjects. Results: The serum zinc level in acne patients were 81.48 ± 14.21 μg/dl and 83.69 ± 12.43 μg/dl in control subjects. There was no statistically significant difference between patients and control subjects (p=0.46).There was a negative correlation between acne severity and serum zinc levels but there was no statistically significant (r=-0.024, p=0.88). Conclusion: The results of our study revealed no relation between serum zinc levels and acne. Further studies are needed.