Veritas temporis filia est: Truth is the daughter of time

N. Pržulj, D. Perović, M. Mirosavljević, M. Nožinić
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Abstract

In 1865, Gregor Mendel presented the lectures 'Experiments in Plant Hybridization' concerning his results from cross-breeding experiments with different types of garden pea, performed in his monastery garden in Brno. Mendel studied easily observed pairs of opposite traits, such as purple or white flower, and discovered dominant and recessive traits. He concluded that parents pass separate and distinct factors (today called genes) on to their offspring that are responsible for inherited traits. However, the scientific community did not understand that; indeed it was the beginning of what becomes genetics. The lectures published in 1866, Mendel sent to more than 30 biologists across Europe, but almost no one commented them. In the next 35 years, these papers were only three times cited. The genetics became more important at the beginning of the 20th century, when three different research groups (Hugo de Vries, Carl Erich Correns and Erich von Tschermak with their co-workers) independently re-discovered Mendel's Laws of inheritance. However, as soon as the work was rediscovered, it created controversy. The closeness of Mendel's experimental observations to those predicted by his theories has led to numerous articles and ongoing debate about whether the data could have been obtained in the published form without some falsification. There have been many plausible arguments made for and against this view by a range of eminent geneticists and statisticians. Some have gone so far, as to suggest that the theories ensued from Mendel's two laws were not even correctly formulated in his original paper. The strongest supporters of Mendel's theory became biologist William Bateson and zoologist and geneticist Thomas Hunt Morgan. Morgan argued that genes are located on chromosomes and that the cells chromosomes hold the actual hereditary material, thus created what is now known as classical genetics. For his discovery concerning the role play by the chromosome in heredity, Morgan received the Nobel Prize in 1933. As the architect of genetic experimental and statistical analysis, Mendel remains the acknowledged father of genetics.
真理是时间的女儿
1865年,格里高尔·孟德尔发表了题为《植物杂交实验》的演讲,内容涉及他在布尔诺修道院花园里用不同类型的豌豆进行杂交实验的结果。孟德尔研究了容易观察到的成对的相反性状,如紫色或白色的花,并发现了显性和隐性性状。他得出的结论是,父母将独立而独特的因素(今天称为基因)传递给后代,这些因素负责遗传特征。然而,科学界并不理解这一点;事实上,这是遗传学的开端。孟德尔的讲稿于1866年出版,他把讲稿寄给了欧洲各地的30多位生物学家,但几乎没有人发表评论。在接下来的35年里,这些论文只被引用了三次。遗传学在20世纪初变得更加重要,当时三个不同的研究小组(雨果·德·弗里斯、卡尔·埃里希·科伦斯和埃里希·冯·切尔马克及其同事)独立地重新发现了孟德尔的遗传定律。然而,这幅作品一被重新发现,就引发了争议。孟德尔的实验观察结果与他的理论所预测的结果非常接近,这导致了大量的文章和持续的争论,即这些数据是否可以在没有一些伪造的情况下以出版的形式获得。许多著名的遗传学家和统计学家对这一观点提出了许多似是而非的论点。有些人走得更远,甚至认为孟德尔的两个定律所产生的理论甚至没有在他最初的论文中正确地表述出来。孟德尔理论最坚定的支持者是生物学家威廉·贝特森和动物学家兼遗传学家托马斯·亨特·摩根。摩根认为,基因位于染色体上,而细胞染色体保存着实际的遗传物质,因此创造了现在被称为经典遗传学的东西。由于发现染色体在遗传中所起的作用,摩根于1933年获得诺贝尔奖。作为基因实验和统计分析的缔造者,孟德尔仍然是公认的遗传学之父。
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