Combination of mifepristone and misoprostol in medical abortion in the first trimester of pregnancy

Abstract

Objective. To determine the effectiveness of the method and patient satisfaction after performing a medical abortion to terminate a pregnancy in the first trimester. Methods. In a retrospective analysis, we present the experiences in performing medical abortion at our clinic in the period from October 1, 2020 to October 1, 2021. Mifepristone tablets and misoprostol tablets were administered according to a scheme, adapted to the protocol of the World Health Organization. Results. In a period of one year at our clinic, we treated 189 patients with the combination of mifepristone and misoprostol in order to terminate a pregnancy in the first trimester. Instrumental revision due to residual masses in the uterus after two weeks was performed in 8 patients (4.23%) while the procedure was repeated successfully in 2 patients (1.06%). The efficiency of the method was 95.8%. We had a small number of complications (prolonged genital bleeding, transient fever, vomiting, etc.). Total of 91.4% of respondents were satisfied with the method. Conclusion. Medical abortion in the first trimester of pregnancy is a safe, effective method and especially useful due to the COVID-19 pandemic, because it can be used without hospitalization, within the ambulatory environment, in consultation with the attending gynecologist.