Determination of the Average Daily Intake of Polychlorinated Biphenyl (PCB) in Breastfed Babies in Vali-Asr Hospital, Tehran University of Medical Sciences

Hosein Dalili, F. Nayeri, M. Shariat, Vafa Ghorbansabagh, Zeinab Kavyani
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引用次数: 1

Abstract

Objective: Breast milk is rich in fat. Toxins, pollutants, drugs, and allergens, especially lipophilic toxins may accumulate in the breast milk; therefore, it can serve as potential source for transferring these toxins to the baby. Dioxins, including polychlorinated biphenyl (PCBs) are among these pollutants. The aim of this study was to determine the average daily intake of PCBs in breastfed babies. Materials and methods: Fifty breast milk samples were collected from breastfeeding mothers whose babies were born in Vali-Asr Hospital, Tehran, Iran in 2014. Each sample was 20 cc and collected within the first 7 days after delivery. PCBs were measured using the GCMass method. We calculated the ADI based on ng/kg/day and compared it with tolerable daily intake (TDI). TDI was considered 20 ng/kg/day according to WHO. Results: The mean PCB concentration was 250.65 ng/gl.w in the collected samples. Among the 6 isomers measured, the concentration of PCB180
德黑兰医科大学Vali-Asr医院母乳喂养婴儿多氯联苯(PCB)日平均摄入量测定
目的:母乳富含脂肪。毒素、污染物、药物和过敏原,特别是亲脂性毒素可能在母乳中积聚;因此,它可以作为将这些毒素转移给婴儿的潜在来源。二恶英,包括多氯联苯(PCBs)就是这些污染物之一。这项研究的目的是确定母乳喂养婴儿多氯联苯的平均每日摄入量。材料与方法:收集2014年在伊朗德黑兰Vali-Asr医院分娩的母乳母亲50例母乳样本。每个样品为20cc,并在交付后的前7天内收集。采用GCMass法测定多氯联苯。我们根据ng/kg/day计算ADI,并将其与每日耐受摄入量(TDI)进行比较。根据世界卫生组织,TDI被认为是20 ng/kg/天。结果:PCB平均浓度为250.65 ng/gl。W在收集的样品中。测得的6种异构体中PCB180浓度
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