Biosensors: The Future of Diagnostics

International journal of sensor networks and data communications Pub Date : 2016-05-02 DOI:10.4172/2090-4886.S1-E001

D. Ap

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引用次数: 8

Abstract

Biosensors are biological sensing molecules with diverse applications in modern biotechnology for the detection of enzymes, toxins, chemicals and most importantly, pathogens. Biosensors are widely used in various fields like food industry to check the quality and safety; in health care sector for the early detection of heart diseases, lung infections, urinary tract infections and rapid identification of pathogens; in pharmaceutical field for drug discovery. Recently, Carbon nanotube based biosensor has been developed for multiplex detection of foodborne pathogens, especially E. coli and S. aureus with an assay time of 1 min. S. aureus and S. typhimurium are also detected from food samples by a dual-excitation sensing method with detection limits of 16 cfu/ml and 28 cfu/ml respectively. Biosensors have also spread their way into the detection of neurogenerative disorders. SPR biosensing method has been used in detecting Aβ42 and Aβ40 levels in serum, biomarkers for Alzheimers disease with a detection limit of 20pM; In the recent times, biosensors played a vital role in diagnosing UTIs and detecting the associated uropathogen, which helped in prescribing an appropriate antibiotic treatment.

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生物传感器:诊断学的未来

生物传感器是一种生物传感分子，在现代生物技术中有多种应用，用于检测酶、毒素、化学物质，最重要的是病原体。生物传感器广泛应用于食品工业等各个领域，用于检测食品的质量和安全;在卫生保健部门进行心脏病、肺部感染、尿路感染的早期发现和病原体的快速鉴定;在制药领域进行药物发现。近年来，基于碳纳米管的生物传感器被开发用于多种食源性致病菌的检测，特别是大肠杆菌和金黄色葡萄球菌的检测时间为1 min，金黄色葡萄球菌和鼠伤寒沙门氏菌的检测也采用双激发传感方法，检出限分别为16 cfu/ml和28 cfu/ml。生物传感器也被广泛应用于神经系统疾病的检测。SPR生物传感方法已用于检测血清中a β42和a β40水平，检测限为20pM;近年来，生物传感器在诊断尿路感染和检测相关尿路病原体方面发挥了至关重要的作用，这有助于处方适当的抗生素治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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International journal of sensor networks and data communications

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