{"title":"Empirical Likelihood Using External Summary Information","authors":"Lyu Ni, Junchao Shao, Jinyi Wang, Lei Wang","doi":"10.5705/ss.202023.0056","DOIUrl":null,"url":null,"abstract":": Statistical analysis in modern scientific research nowadays has opportunities to utilize external summary information from similar studies to gain efficiency. However, the population generating data for current study, referred to as internal population, is typically different from the external population for summary information, although they share some common characteristics that make efficiency improvement possible. The existing population heterogeneity is a challenging issue especially when we have only summary statistics but not individual-level external data. In this paper, we apply an empirical likelihood approach to estimating internal population distribution, with external summary information utilized as constraints for efficiency gain under population heterogeneity. We show that our approach produces an asymptotically more efficient estimator of internal population distribution compared with the customary empirical likelihood without using any external information, under the condition that the external information is based on a dataset with size larger than that","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.5705/ss.202023.0056","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
: Statistical analysis in modern scientific research nowadays has opportunities to utilize external summary information from similar studies to gain efficiency. However, the population generating data for current study, referred to as internal population, is typically different from the external population for summary information, although they share some common characteristics that make efficiency improvement possible. The existing population heterogeneity is a challenging issue especially when we have only summary statistics but not individual-level external data. In this paper, we apply an empirical likelihood approach to estimating internal population distribution, with external summary information utilized as constraints for efficiency gain under population heterogeneity. We show that our approach produces an asymptotically more efficient estimator of internal population distribution compared with the customary empirical likelihood without using any external information, under the condition that the external information is based on a dataset with size larger than that
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.