2-(((4h-1,2,4-Triazol-4-Yl)Imino)Methyl)Phenol Derived Schiff Bases And Their Pharmacological Importance

Abstract

A facile method has been developed for the synthesis of Schiff bases derived from 4-Amino-1,2,4-triazole with 2-Hydroxybenzaldehyde (Salicylaldehyde) and their complexes with the Mn(II) and V(III) have been synthesized. Derived Metal complexes shown that they have a greater impact than their parent medications. Elemental analysis, IR, and ESR XRD studies have been used to characterize the prepared complexes. The results of the spectroscopic investigations suggested that the metal complexes' have octahedral geometry and the presence of the azomethine nitrogen group in coordination with the metal ion have been projected. Schiff bases and their derived metal complexes have potent biological potential (Antibacterial).