Clinical Application of Fetal Umbilical Vein Doppler Parameters in Maternal Preeclampsia

Abstract

Objective: To observe the changes of fetal umbilical vein (UV) Doppler parameters in pregnant women with preeclampsia (PE) and analyze their pre-dictive values for maternal PE. Methods: Forty-six patients with PE who underwent systematic ultrasound examination in our hospital from December 2017 to May 2021 were included as the subjects, which were divided into two groups according to the severity of the disease (23 cases in each group). And 120 normal pregnant women who underwent health examination in our hospital during the same period were enrolled as the control group. Color Doppler ultrasonography was used to monitor the umbilical vein flow (QUV), left portal vein flow (QLPV), venous catheter flow (QDV), left portal vein (LPV) shunt rate and venous catheter (DV) shunt rate. And the sensitivity and specificity of the related indexes were calculated and analyzed according to the gold standard for clinical diagnosis of PE. Results: As the severity of PE increased, the fetal QUV, QLPV and LPV shunt rates decreased, and the QDV and DV shunt rates increased, with statistically significant differences compared with the control group (P < 0.05). The specificity and sensitivity of the combination of fetal QUV, QLPV, QDV, LPV shunt rate and DV shunt rate in predicting PE were higher than those of the indexes used alone (P < 0.05). Conclusion: The fetal umbilical vein Doppler parameters QUV, QLPV, QDV, LPV shunt rate, and DV shunt rate have some value in predicting PE, but their combination showed greater value, as well as higher diagnostic and clinical significance.