Evaluation of the Protection against Infectious Bursal Disease (IBD) Challenge in Progeny Born to Parents Having Received a Vaccination Program Using a Herpesvirus of Turkey-Infectious Bursal Disease (HVT-IBD) Vector Vaccine
S. Lemiere, Jean-Claude Gauthier, A. Kodjo, Laure Vinit, A. Delvecchio, F. Prandini
{"title":"Evaluation of the Protection against Infectious Bursal Disease (IBD) Challenge in Progeny Born to Parents Having Received a Vaccination Program Using a Herpesvirus of Turkey-Infectious Bursal Disease (HVT-IBD) Vector Vaccine","authors":"S. Lemiere, Jean-Claude Gauthier, A. Kodjo, Laure Vinit, A. Delvecchio, F. Prandini","doi":"10.4236/WJV.2013.32008","DOIUrl":null,"url":null,"abstract":"Broiler breeder \nvaccination against IBD is usually based on the injection of at least one \ninactivated vaccine in oil adjuvant, typically included in a combined vaccine. Priming using one or \nseveral IBD vaccine (s) \nhas been the most common \nway to immunize the breeders so far. In summary, protection against vvIBD \nchallenge in chicks of one commercial genetic line vaccinated in ovo with the HVT-IBD vector vaccine \nwas demonstrated. The parents’ IBD vaccination program, using the HVT-IBD vector vaccine \nalone, the HVT-IBD vector vaccine plus IBD inactivated vaccine, and inactivated IBD vaccine alone, did not \nimpair their progeny’s in ovo HVT-IBD \nvector vaccine take and subsequent protection against vvIBD virus challenge. An \nadvantage in terms of immunization of the progeny against vvIBD was shown in \nthe chicks born to breeders vaccinated with the HVT-IBD vaccine as a primer, as \ncompared to breeders vaccinated with the inactivated vaccine alone. High level \nof IBD maternally-derived antibodies transmitted to the progeny by their parents \ninduces together with an early onset of immunity by in ovo injection of a HVT-IBD vector vaccine clinical protection, \nas monitored on bursas, after vvIBD virus challenge.","PeriodicalId":57190,"journal":{"name":"疫苗(英文)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2013-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"疫苗(英文)","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4236/WJV.2013.32008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
Broiler breeder
vaccination against IBD is usually based on the injection of at least one
inactivated vaccine in oil adjuvant, typically included in a combined vaccine. Priming using one or
several IBD vaccine (s)
has been the most common
way to immunize the breeders so far. In summary, protection against vvIBD
challenge in chicks of one commercial genetic line vaccinated in ovo with the HVT-IBD vector vaccine
was demonstrated. The parents’ IBD vaccination program, using the HVT-IBD vector vaccine
alone, the HVT-IBD vector vaccine plus IBD inactivated vaccine, and inactivated IBD vaccine alone, did not
impair their progeny’s in ovo HVT-IBD
vector vaccine take and subsequent protection against vvIBD virus challenge. An
advantage in terms of immunization of the progeny against vvIBD was shown in
the chicks born to breeders vaccinated with the HVT-IBD vaccine as a primer, as
compared to breeders vaccinated with the inactivated vaccine alone. High level
of IBD maternally-derived antibodies transmitted to the progeny by their parents
induces together with an early onset of immunity by in ovo injection of a HVT-IBD vector vaccine clinical protection,
as monitored on bursas, after vvIBD virus challenge.