J. Reyna-Figueroa, Diana PerezPeña-Rosas, Patricia Galindo-Delgado, A. E. Limón-Rojas, V. Madrid-Marina
{"title":"Association between an Incomplete Vaccination Schedule and Nosocomial Sepsis among Children with Cancer","authors":"J. Reyna-Figueroa, Diana PerezPeña-Rosas, Patricia Galindo-Delgado, A. E. Limón-Rojas, V. Madrid-Marina","doi":"10.4236/WJV.2013.31002","DOIUrl":null,"url":null,"abstract":"Background: Patients with cancer constitute a \nspecial group where immunization programs are often interrupted to begin \ntreatment with chemotherapy. Sepsis is one of the main complications in this \ngroup. Methods: A hospital-based case-control study matched by age was carried out among \nsubjects ≤ 9 years of age \nwith cancer diagnosis. Children with cancer without sepsis and children with \nsurgical pathology were included as controls; children with sepsis were included \nas cases. A bivariate logistic regression was used to determine the factors \nassociated to nosocomial sepsis, and odds ratios were calculated with 95% \nconfidence intervals. The percentage of attributable risk was calculated for \nthe variables included in the final model. Results: Nineteen children with cancer and sepsis and 83 controls were included. Twelve \n(44%) caseshad an incomplete vaccination schedule according to their age. The \nassociation force between incomplete schedule and sepsis was 10.1 (95% CI, 3 - 36; p Conclusions: Approximately, 20% to 65% of the cases of serious nosocomial infection \ncan be associated to an incomplete vaccination schedule. Strategies should be \nimplemented to improve the general pediatric population’s vaccination status \nbefore a serious disease, such as cancer or another chronic condition \npreventing the application of vaccines, develops.","PeriodicalId":57190,"journal":{"name":"疫苗(英文)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2013-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"疫苗(英文)","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4236/WJV.2013.31002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
Abstract
Background: Patients with cancer constitute a
special group where immunization programs are often interrupted to begin
treatment with chemotherapy. Sepsis is one of the main complications in this
group. Methods: A hospital-based case-control study matched by age was carried out among
subjects ≤ 9 years of age
with cancer diagnosis. Children with cancer without sepsis and children with
surgical pathology were included as controls; children with sepsis were included
as cases. A bivariate logistic regression was used to determine the factors
associated to nosocomial sepsis, and odds ratios were calculated with 95%
confidence intervals. The percentage of attributable risk was calculated for
the variables included in the final model. Results: Nineteen children with cancer and sepsis and 83 controls were included. Twelve
(44%) caseshad an incomplete vaccination schedule according to their age. The
association force between incomplete schedule and sepsis was 10.1 (95% CI, 3 - 36; p Conclusions: Approximately, 20% to 65% of the cases of serious nosocomial infection
can be associated to an incomplete vaccination schedule. Strategies should be
implemented to improve the general pediatric population’s vaccination status
before a serious disease, such as cancer or another chronic condition
preventing the application of vaccines, develops.