Larviciding potency of water and ethanol extracts of Phytolacca dodecandra (L’ Herit) on Anopheles gambiae (Diptera: Culicidae)

Abstract

Introduction: Plant extracts are an attractive target for search of effective malaria vector control agents. The reason for this is that they present a cost effective, target specific and bio-degradable insecticides. The other reason is that they posses varied phytochemical contents that vectors are unlikely to develop resistance to very soon. In this study, we report on effectiveness of ethanol and water extracts of Phytolacca dodecandra (L’ Herit) against Anopheles gambiae (Diptera: Culicidae) larvae. Methods: Crude ethanol and water extracts of leaves (shoot and midsection) and mature green fruits of P. dodecandra were scrutinized for larvicidal activity against 1 st to 4 th instar larvae of An. gambiae . Larvicidal bioassays were conducted and effectiveness evaluated using the >80% as per the WHO methods and threshold respectively. ANOVA analyses were performed for statistical justifications of the larvicidal property with P considered significant at p 80%. We recommend that additional refinement and tests need to be done before commercial exploitation as a malaria vector larvicide.