Coagulability state in histopathologicaly and radiologicaly approved ovarian endomertiosis

IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL

Rawal Medical Journal Pub Date : 2023-01-01 DOI:10.5455/rmj20221126063638

Zahraa Alzuhairi, T. Fadhel, Intisar Hasan

{"title":"Coagulability state in histopathologicaly and radiologicaly approved ovarian endomertiosis","authors":"Zahraa Alzuhairi, T. Fadhel, Intisar Hasan","doi":"10.5455/rmj20221126063638","DOIUrl":null,"url":null,"abstract":"Objective: To determine the association between endometriosis and clotting abnormalities in relation to histopathological and ultrasound diagnosis. Methodology: This cross-sectional study included 125 females with endometriosis seen at Baqubah teaching hospital from April 2021 and June 2022. The women's ages varied from 21 to 43 years. Seventy-five had ultrasound-detected ovarian cysts, 48 had MRI-confirmed ovarian endometriosis, and 50 normal women served as controls. All women had thrombin time, prothrombin time, activated partial thromboplastin time, D-dimer, plasma fibrinogen, and INR tested. Results: The study had 125 females with mean age of 29±6 years. Histologically, 20.8% had endometrial gland and stroma and 11.2% had endometrial stroma. Endometriosis reduced PT, PTT, TT, and INR, but increased fibrinogen and D. dimer. There was significant association between ultrasound diagnosis and histopathological diagnosis of endometriosis. Conclusion: PT, PTT, INR, Fibrinogen, and D. dimer levels differ between histology and ultrasonography endometriosis diagnoses in women. Endometriosis patients showed greater fibrinogen and D. dimer levels and reduced PT, PTT, TT, and INR (INR).","PeriodicalId":20844,"journal":{"name":"Rawal Medical Journal","volume":"1 1","pages":""},"PeriodicalIF":0.4000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rawal Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5455/rmj20221126063638","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: To determine the association between endometriosis and clotting abnormalities in relation to histopathological and ultrasound diagnosis. Methodology: This cross-sectional study included 125 females with endometriosis seen at Baqubah teaching hospital from April 2021 and June 2022. The women's ages varied from 21 to 43 years. Seventy-five had ultrasound-detected ovarian cysts, 48 had MRI-confirmed ovarian endometriosis, and 50 normal women served as controls. All women had thrombin time, prothrombin time, activated partial thromboplastin time, D-dimer, plasma fibrinogen, and INR tested. Results: The study had 125 females with mean age of 29±6 years. Histologically, 20.8% had endometrial gland and stroma and 11.2% had endometrial stroma. Endometriosis reduced PT, PTT, TT, and INR, but increased fibrinogen and D. dimer. There was significant association between ultrasound diagnosis and histopathological diagnosis of endometriosis. Conclusion: PT, PTT, INR, Fibrinogen, and D. dimer levels differ between histology and ultrasonography endometriosis diagnoses in women. Endometriosis patients showed greater fibrinogen and D. dimer levels and reduced PT, PTT, TT, and INR (INR).

查看原文本刊更多论文

组织病理学和放射学证实的卵巢子宫内膜异位症的凝血状态

目的:探讨子宫内膜异位症与凝血异常的关系及组织病理学和超声诊断。方法:本横断面研究纳入了2021年4月至2022年6月在Baqubah教学医院就诊的125名子宫内膜异位症女性。这些女性的年龄从21岁到43岁不等。75名女性患有超声检查出的卵巢囊肿，48名患有核磁共振证实的卵巢子宫内膜异位症，50名正常女性作为对照。所有女性均进行凝血酶时间、凝血酶原时间、活化部分凝血活酶时间、d -二聚体、血浆纤维蛋白原和INR检测。结果:共纳入125例女性，平均年龄29±6岁。组织学上，子宫内膜腺及间质占20.8%，子宫内膜间质占11.2%。子宫内膜异位症降低PT、PTT、TT和INR，但增加纤维蛋白原和d二聚体。超声诊断与子宫内膜异位症的病理诊断有显著相关性。结论:PT、PTT、INR、纤维蛋白原、d二聚体水平在子宫内膜异位症的病理诊断和超声诊断中存在差异。子宫内膜异位症患者纤维蛋白原和d二聚体水平升高，PT、PTT、TT和INR (INR)降低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Rawal Medical Journal MEDICINE, GENERAL & INTERNAL-

CiteScore

0.70

自引率

0.00%

发文量

期刊介绍： RMJ is a general Medicine publication and accepts oorigial articles, editorials, case reports and commentaries. It aims to dessiminate medical knowldge to professional community.