Rare cases of Langerhans cell histiocytosis

Abstract

Langerhans cell histiocytosis (LCH) is a group of disorders character-ized by proliferation of cells of mononuclear phagocytic system. In this study rare cases of Langerhans cell histiocytosis (LCH) were diagnosed. These patients had bony defects, proptosis, bilateral cervical lymphadenopathy in one case. The second case had cheek swelling, hepatosplenomegaly, skull and cheek swellings along with proptosis. The characteristic Langerhans cells were present on cytology for both cases. Hence these cases were diagnosed in both cases as Langerhans cell histiocytosis (LCH) based on clinical, radiological and cytological features.