Sickle cell disease status among school adolescents and their tribal community in South Gujarat

The Internet journal of pediatrics and neonatology Pub Date : 2009-12-31 DOI:10.5580/20c8

Bipin Vasava, Rajesh K. Chudasama, Naresh R Godara, R. Srivastava

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引用次数: 4

Abstract

Objectives: to create awareness, to screen samples of school adolescents and then to reach their community through them by doing surveillance for sickle cell disease. Design: Field based cross-sectional study. Settings: St Xavier`s high school and Vanraj high school of Umarpada taluka of Surat district. Subjects: School adolescents, their parents and friends. Method: After taking permission from school authority, blood samples of 948 school adolescents were taken for DTT test and then for electrophoresis. Blood samples of motivated parents and friends of those adolescents found positive for DTT was taken in subsequent visit and results were communicated to them. Results: Blood samples of 948 school adolescents, out of 1081 were tested for DTT test. It was positive in 242 samples, giving a prevalence of 25.5% for sickle cell disease. On subjecting the positive blood samples to electrophoresis, the proportion of sickle cell trait and sickle cell disease was found to be 92% and 8% respectively. Then electrophoresis was done in 64 parents and friends, 24 (37.5%) of them were found positive of which, 14 (58%) were having sickle cell trait and 10 (42%) having sickle cell disease. Conclusion: approaching community can be possible through school adolescents for conduction of surveillance of sickle cell anemia

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南古吉拉特邦学校青少年及其部落社区的镰状细胞病状况

目标:提高认识，筛选学校青少年样本，然后通过他们监测镰状细胞病，向他们的社区宣传。设计:基于实地的横断面研究。背景:苏拉特地区Umarpada taluka的圣泽维尔高中和Vanraj高中。研究对象:在校青少年、他们的父母和朋友。方法:经校方同意，抽取948名在校青少年血样进行DTT检测和电泳。这些青少年的父母和朋友在随后的访问中采集了DTT阳性的血液样本，并将结果告知他们。结果:对1081名在校生中的948人进行了DTT检测。242个样本呈阳性，说明镰状细胞病的患病率为25.5%。对阳性血样进行电泳，发现镰状细胞性状和镰状细胞病的比例分别为92%和8%。对64名父母和朋友进行电泳，其中阳性24人(37.5%)，有镰状细胞性状14人(58%)，有镰状细胞病10人(42%)。结论:通过学校青少年开展镰状细胞性贫血的社区监测是可行的

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The Internet journal of pediatrics and neonatology

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