Retrospective Evaluation of the Association of Impaired Fasting Glucose and Hyperlipidemia in Patients Applying to the Family Medicine Outpatient Clinic

Abstract

ABS TRACT Objective: Family physicians have an important place in early diagnosis and follow-up diabetes and prevention of metabolic disorders that may develop later. We examined the association of impaired fasting glucose (IFG) which is the early stage of diabetes, and lipid metabolism disorder. Material and Methods: Our retrospective study included 993 patients without known diabetes, dyslipidemia, cardiovascular disease who applied to Family medicine outpatient clinic. De- mographic characteristics of the cases, fasting plasma glucose (FPG), total cholesterol, triglyceride, high density lipoprotein (HDL), low den- sity lipoprotein (LDL) and hemoglobin A1c (HbA1c) parameters were evaluated. Result: Of the study participants, 67.9% were women and 41.6% had IFG. LDL in 35.4% (n=352) of cases; 33.6% (n=334) of total cholesterol; 26.2 % (n=260) had high triglyceride values; HDL was found to low in 51.1% (n=507). The rate of high triglyceride levels and mean age of patients with IFG were higher than those with nor- mal FPG levels (p<0.001) (p<0.001). The incidence of IFG in men was higher than women (p<0.05). HbA1c levels of patients with IFG were higher than with normal FPG (p<0.001). The mean age of the patients with high LDL, total cholesterol and triglyceride levels were found higher than patients with normal values (p<0.001). The HbA1c levels of the cases with abnormal triglyceride levels were higher than those with normal levels (p<0.05). Conclusion: We observed data indicating that lipid metabolism disorder may start together with glucose metabolism in IFG period. In preventive medicine practices, it may be clinically important to identify patients at risk in early period and fol- low them in terms of glucose and lipid metabolism.