Novel Indices for Lumbar Discectomy: Systemic Immune Inflammation Index, Systemic Inflammatory Response Index, Multi Inflammatory Index, and Prognostic Nutrition Index.

IF 0.9 4区医学 Q4 CLINICAL NEUROLOGY

Turkish neurosurgery Pub Date : 2024-01-01 DOI:10.5137/1019-5149.JTN.42769-22.2

Samil Dikici

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Abstract

Aim: To evaluate systemic immune inflammation index (SII), systemic inflammatory response index (SIRI), multi-inflammatory index (MII), and prognostic nutrition index (PNI), and to compare them with the previously reported inflammation-related hematologic index in lumbar discectomy (LD).

Material and methods: This was a retrospective, cross-sectional, single-center study with 105 consecutive patients who underwent surgery for LD. The study comprised three groups: Group I included data from healthy participants, Group II included data before LD, and Group III included data after LD. We analyzed mean platelet volume (MPV), platelet-lymphocyte ratio (PLR), neutrophil-lymphocyte ratio (NLR), SIRI, SII, MII, and PNI, in comparison with the Roland-Morris Disability Questionnaire (RMDQ), Oswestry Disability Index (ODI), and Visual analog scale for leg (VASLeg).

Results: CRP and MPV were similar for the preoperative and postoperative periods (p=0.489). In the postoperative measurements, NLR, PLR, SII, and SIRI increased (p < 0.0001). On the contrary, PNI decreased with LD (p < 0.0001). NLR (p < 0.001), SII (p < 0.001), and SIRI (p < 0.001) were the valuable indices for LD. PLR (p < 0.001), MII-1 (p=0.004), and MII-2 (p < 0.001) also predicted LD. ODI, RMDQ, and VASLeg correlated with MII-1, MII-2, and SIRI.

Conclusion: LD's most substantial and valuable indices were NLR, SII, and SIRI. Regarding superiority to SII and NLR, SIRI showed significant agreement with the scales and drew a more appropriate marker profile for LD than MII-1, MII-2, and PNI.

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腰椎间盘切除术的新指标：系统免疫炎症指数、系统炎症反应指数、多种炎症指数和预后营养指数。

目的：评估腰椎间盘切除术（LD）中的全身免疫炎症指数（SII）、全身炎症反应指数（SIRI）、多重炎症指数（MII）和预后营养指数（PNI），并将其与之前报道的炎症相关血液学指数进行比较：这是一项回顾性、横断面、单中心研究，研究对象为连续接受腰椎间盘切除手术的 105 名患者。研究分为三组：第一组包括健康参与者的数据，第二组包括 LD 前的数据，第三组包括 LD 后的数据。我们分析了平均血小板体积（MPV）、血小板-淋巴细胞比值（PLR）、中性粒细胞-淋巴细胞比值（NLR）、SIRI、SII、MII 和 PNI，并与罗兰-莫里斯残疾问卷（RMDQ）、Oswestry 残疾指数（ODI）和腿部视觉模拟量表（VASLeg）进行了比较：术前和术后的 CRP 和 MPV 相似（P=0.489）。在术后测量中，NLR、PLR、SII 和 SIRI 均有所增加（P < 0.0001）。相反，PNI 随 LD 下降（p < 0.0001）。NLR（p < 0.001）、SII（p < 0.001）和 SIRI（p < 0.001）是对 LD 有价值的指数。PLR（p < 0.001）、MII-1（p=0.004）和 MII-2（p < 0.001）也能预测 LD。ODI、RMDQ和VASLeg与MII-1、MII-2和SIRI相关：结论：LD 最有价值的指标是 NLR、SII 和 SIRI。结论：LD 最有价值的指标是 NLR、SII 和 SIRI。与 SII 和 NLR 相比，SIRI 与量表有显著的一致性，比 MII-1、MII-2 和 PNI 更适合 LD。

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来源期刊

Turkish neurosurgery 医学-临床神经学

CiteScore

1.50

自引率

12.50%

发文量

126

审稿时长

2 months

期刊介绍： Turkish Neurosurgery is a peer-reviewed, multidisciplinary, open access and totally free journal directed at an audience of neurosurgery physicians and scientists. The official language of the journal is English. The journal publishes original articles in the form of clinical and basic research. Turkish Neurosurgery will only publish studies that have institutional review board (IRB) approval and have strictly observed an acceptable follow-up period. With the exception of reference presentation, Turkish Neurosurgery requires that all manuscripts be prepared in accordance with the Uniform Requirements for Manuscripts Submitted to Biomedical Journals.