Evaluation of mean platelet volume as a predictor of gastric disorders

Abstract

Aim: Gastric disorders present in a wide range, including malignant and benign diseases of the upper gastrointestinal system. Increased MPV levels are associated with inflammation. The goal of this study was to determine the diagnostic importance of MPV in gastric disorders and evaluate level of MPV in patients that underwent upper gastrointestinal endoscopy. Materials and Methods: Patients who had undergone endoscopy and shown to have a gastric disorder with blood count performed were included in the study. Only one surgeon performed all of the endoscopies. MPV value, platelet count, hemoglobin and white blood cell count levels were analyzed. Results: 116 patients were included in the study. Mean age of all patients was 47,8±16,4. Mean value of MPV was determined to be 7,79±1,21, within the range of 5,85 to 12,5 fL. There was no significant correlation between diagnoses and MPV levels (P>0,05). Additionally, there was no significant difference in MPV levels in histopathological diagnoses groups (p>0,05). There was a highly negative correlation between platelet count and MPV levels in a Scatter Plot correlation graph (r=0,083). Conclusions: MPV is a frequently used hematological parameter that indicates platelet function and activity affected by inflammation. It was hypothesized that changes in MPV levels could be associated with gastric disorders. Statistical analysis of the data revealed there was no association between MPV and gastric disorders. It is suggested that MPV is not a suitable marker to determine gastric disorders, however further larger studies can be useful to determine the importance of MPV such a context.