Atya Hassan Atya Hassan, Sana Gul Sana Gul, Taswar Ali Chandio and Muhammad Ali Minhas Taswar Ali Chandio and Muhammad Ali Minhas
{"title":"Electrochemical and Computational Study of Copper Histidine Complex via Cyclic Voltammetry","authors":"Atya Hassan Atya Hassan, Sana Gul Sana Gul, Taswar Ali Chandio and Muhammad Ali Minhas Taswar Ali Chandio and Muhammad Ali Minhas","doi":"10.52568/001077/jcsp/44.04.2022","DOIUrl":null,"url":null,"abstract":"L-Histidine regulates body function and involve in the synthesis of hemoglobin, repairing of tissues and strengthens of immune system. In this study, Cyclic Voltammetry (CV) is used with 0.1 M Potassium Chloride as a supporting electrolyte to determine the accurate metal ligand ratio between Cu+2 and L-Histidine. In CV potential window is set between +0.6 to -0.4V to record theVoltammogram. Voltammograms were recorded by varying scan rate from 50mV/s to 300mV/s. Cyclic Voltammetry is used to analyzed the interfacial performance of the complex and repeated CyclicVoltammograms (07 cycles) were recorded at Glassy Carbon Electrode (GCE), that shows no change in peak current intensity of both anodic and cathodic peak. Further, neither pre nor any post peak was observed. These interpretation express that reactant and product are not involve in the adsorption-desorption process at the surface of Glassy Carbon Electrode (GCE). These remarks suggest that it is diffusion controlled process in the above mentioned system. The interaction of Cu+2 and L-Histidine were not reported before through Cyclic Voltammetry. Furthermore, in this study structure of Cu+2 vs. L-Histidine complex is investigated from a theoretical perspective. Optimization of Cu+2 vs. L-Histidine complex was carried out by DFT method and result verifies that stable structure of Cu+2 vs. L-Histidine complex exist as square planar structure in 1:2 ratio respectively. The computed structure has correlation with experimental results and Voltammogram of 1:2 ratio complex of Cu+2 vs. L-Histidine suggested that it exist in Square planar geometry.","PeriodicalId":17253,"journal":{"name":"Journal of the chemical society of pakistan","volume":null,"pages":null},"PeriodicalIF":0.6000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the chemical society of pakistan","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.52568/001077/jcsp/44.04.2022","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 1
Abstract
L-Histidine regulates body function and involve in the synthesis of hemoglobin, repairing of tissues and strengthens of immune system. In this study, Cyclic Voltammetry (CV) is used with 0.1 M Potassium Chloride as a supporting electrolyte to determine the accurate metal ligand ratio between Cu+2 and L-Histidine. In CV potential window is set between +0.6 to -0.4V to record theVoltammogram. Voltammograms were recorded by varying scan rate from 50mV/s to 300mV/s. Cyclic Voltammetry is used to analyzed the interfacial performance of the complex and repeated CyclicVoltammograms (07 cycles) were recorded at Glassy Carbon Electrode (GCE), that shows no change in peak current intensity of both anodic and cathodic peak. Further, neither pre nor any post peak was observed. These interpretation express that reactant and product are not involve in the adsorption-desorption process at the surface of Glassy Carbon Electrode (GCE). These remarks suggest that it is diffusion controlled process in the above mentioned system. The interaction of Cu+2 and L-Histidine were not reported before through Cyclic Voltammetry. Furthermore, in this study structure of Cu+2 vs. L-Histidine complex is investigated from a theoretical perspective. Optimization of Cu+2 vs. L-Histidine complex was carried out by DFT method and result verifies that stable structure of Cu+2 vs. L-Histidine complex exist as square planar structure in 1:2 ratio respectively. The computed structure has correlation with experimental results and Voltammogram of 1:2 ratio complex of Cu+2 vs. L-Histidine suggested that it exist in Square planar geometry.
期刊介绍:
This journal covers different research areas in the field of Chemistry. These include; Analytical Chemistry, Applied Chemistry, Biochemistry, Environmental Chemistry, Industrial Chemistry, Inorganic Chemistry, Organic Chemistry and Physical Chemistry. The journal publishes full length articles and Reviews from researchers in academia in addition to featuring comments. Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry.