Link between Periodontal Diseases, Inflammatory Markers and Preterm Low Birth Weight Infants

Clinical Medicine Insights-Reproductive Health Pub Date : 2010-01-01 DOI:10.4137/CMRH.S5886

M. El-Gharib, M. Nassar, M. T. Elabyary, T. M. Elhawary, S. H. Elshourbagy

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引用次数: 6

Abstract

Objective To scrutinize the assumed association between chronic periodontal disease and preterm low birth weight (PTLB) infants. Design Prospective study. Setting Tanta University Hospital. Patients The study incorporated 200 pregnant women in the first stage of labor of a single baby with intact membranes. A hundred women had definite preterm labor and delivered, later live infants whose birth weight were < 2500 g and 100 women with full term labor and delivered, later live infants weighting ≥2500 g. Intervention All patients included in the study were subjected to history taking, general, obstetrical examination and periodontal evaluation. The levels of IL-6 and TNF-α were measured in gingival cervicular fluid, maternal serum and amniotic fluid using ELISA technique. Results A significant association between chronic periodontal disease and preterm low birth weight infants. Conclusion Screening of pregnant women chronic periodontal disease seems to be a helpful prediction and consequently prevention of preterm labour.

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牙周病、炎症标志物与早产低体重儿之间的联系

目的探讨慢性牙周病与早产儿低出生体重(PTLB)的关系。前瞻性研究。坦塔大学附属医院该研究纳入了200名处于产程第一阶段的孕妇，其中有一个胎膜完好的婴儿。100名妇女有明确的早产和分娩，后来活产婴儿出生体重< 2500克和100名妇女足月分娩，后来活产婴儿体重≥2500克。所有纳入研究的患者均接受病史、一般检查、产科检查和牙周评估。采用酶联免疫吸附法(ELISA)检测龈宫颈液、母体血清和羊水中IL-6、TNF-α水平。结果慢性牙周病与早产儿低出生体重有显著相关性。结论孕妇慢性牙周病筛查有助于预测和预防早产。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Medicine Insights-Reproductive Health OBSTETRICS & GYNECOLOGY-

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： Clinical Medicine Insights: Reproductive Health is a peer reviewed; open access journal, which covers all aspects of Reproduction: Gynecology, Obstetrics, and Infertility, spanning both male and female issues, from the physical to the psychological and the social, including: sex, contraception, pregnancy, childbirth, and related topics such as social and emotional impacts. It welcomes original research and review articles from across the health sciences. Clinical subjects include fertility and sterility, infertility and assisted reproduction, IVF, fertility preservation despite gonadotoxic chemo- and/or radiotherapy, pregnancy problems, PPD, infections and disease, surgery, diagnosis, menopause, HRT, pelvic floor problems, reproductive cancers and environmental impacts on reproduction, although this list is by no means exhaustive Subjects covered include, but are not limited to: • fertility and sterility, • infertility and ART, • ART/IVF, • fertility preservation despite gonadotoxic chemo- and/or radiotherapy, • pregnancy problems, • Postpartum depression • Infections and disease, • Gyn/Ob surgery, • diagnosis, • Contraception • Premenstrual tension • Gynecologic Oncology • reproductive cancers • environmental impacts on reproduction, • Obstetrics/Gynaecology • Women''s Health • menopause, • HRT, • pelvic floor problems, • Paediatric and adolescent gynaecology • PID