Factors Associated with Pregnancy Outcomes in Hypertensive Pregnant Women in a District Hospital in Benin

Saizonou Jacques, G. Yolaine, Kpozehouen Alphonse, Tawo Mondoukpè, Ouendo Edgard-Marius
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Abstract

Introduction: Hypertension is a major cause of maternal and perinatal morbidity and mortality. This study aims at exploring the outcomes of pregnancy and associated factors in hypertensive pregnant women in Comè district hospital from 2014 to 2016. Methods: This is a retrospective, analytical study carried out in June 2016, involving a total of 345 hypertensive patients. Socio-de-mographic and medical features, including pregnancy and foetal outcomes pa-rameters, were recorded in the case files. Top-down stepwise logistic regression was performed at the 5% threshold. Results: The frequency of hypertensive disorders during pregnancy was estimated at 7.32% and unfavourable outcomes at 35.65%. The adverse maternal outcomes recorded were postpartum death and haemorrhage whereas adverse foetal issues were prematurity, low birth weight, low Apgar scores, stillbirth and death. Factors statistically associated with pregnancy outcome were paucigravida (OR = 2.01 ([1.05 -3.88]), p = 0.035), history of stillbirth (OR = 4.75 ([1.01 - 22.1]), p = 0.048) and anticonvulsant therapy (OR = 0.32 ([0.19 - 0.54]), p < 0.001). Conclusion: Adequate monitoring via Antenatal Care (ANC) check-ups, timely recourse to care and an effective communication strategy should reduce hypertensive disorders incidence and adverse outcomes in pregnant women.
贝宁某地区医院高血压孕妇妊娠结局的相关因素
高血压是孕产妇和围产期发病和死亡的主要原因。本研究旨在探讨Comè区医院2014 - 2016年高血压孕妇妊娠结局及相关因素。方法:回顾性分析研究于2016年6月开展,共纳入345例高血压患者。社会人口统计学和医学特征,包括妊娠和胎儿结局参数,都记录在病例档案中。在5%阈值处进行自上而下逐步逻辑回归。结果:妊娠期高血压疾病发生率为7.32%,不良结局发生率为35.65%。记录的不良产妇结局是产后死亡和出血,而不良胎儿问题是早产、低出生体重、低阿普加评分、死产和死亡。与妊娠结局相关的因素有:无妊娠(OR = 2.01 ([1.05 -3.88]), p = 0.035)、死产史(OR = 4.75 ([1.01 - 22.1]), p = 0.048)和抗惊厥治疗(OR = 0.32 ([0.19 - 0.54]), p < 0.001)。结论:通过产前保健(ANC)检查进行充分的监测,及时求助于护理和有效的沟通策略可以减少孕妇高血压疾病的发病率和不良后果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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