Effect of leaf extracts of Dendrosicyos socotrana and Jatropha unicostata on the viability of Echinococcus granulosus protoscoleces

Q3 Agricultural and Biological Sciences
Abdul Kadir R. A. Barzinji, R. Mothana, A. Nasher
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引用次数: 30

Abstract

The present work evaluates the effect of aqueous and methanolic extracts of Dendrosicyos socotrana and Jatropha unicostata on the viability of Echinococcus granulosus protoscoleces in vitro, and on the development of secondary hydatid cysts, in vivo. Three different concentrations of each leaf extract were used. Concentrations of 5000 and 1000 μg/mL, for D. socotrana and J. unicostata, respectively, exhibited the highest protoscolicidal activity, significantly reducing and/or stopping protoscolex viability. Oral and intraperitoneal administration of the extracts in white mice invoked noticeable inhibitory effects on the in vivo development of secondary hydatid cysts. These effects were compared with those of albendazole sulfoxide, a commonly used treatment for hydatidosis.
石斛和麻疯树叶提取物对细粒棘球蚴原头节活力的影响
本研究评估了水提液和甲醇提液在体外对细粒棘球蚴原头节活力的影响,以及在体内对继发性包虫囊肿发育的影响。每种叶子提取物使用三种不同浓度。在5000 μg/mL和1000 μg/mL浓度下,socotrana和jj . unicostata的原头节活性最高,可显著降低和/或停止原头节活性。口服和腹腔给药提取物对小鼠体内继发性包虫囊肿的发育有明显的抑制作用。这些效果与阿苯达唑亚砜比较,阿苯达唑亚砜是一种常用的治疗包虫病的药物。
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来源期刊
Eurasian Journal of Biosciences
Eurasian Journal of Biosciences Agricultural and Biological Sciences-Agricultural and Biological Sciences (all)
CiteScore
1.20
自引率
0.00%
发文量
0
期刊介绍: EurAsian Journal of BioSciences (Abbrev. Eurasia J Biosci or EJOBIOS) is an international, refereed electronic journal. It publishes the results of original research in the field of biological sciences restricted tomorphology, physiology, genetics, taxonomy, ecology and biogeography of both prokaryotic and eucaryotic organisms. The journal encourages submission of manuscripts dealing with plant biology, animal biology, plant physiology, microbiology, hydrobiology, ecology and environmental science, ethnobiology, biodiversity and conservation biology. EurAsian Journal of BioSciences publishes original articles in the following areas: -Agriculture, Fisheries & Food -Anatomy & Morphology -Behavioural Sciences -Biology, Biochemistry and Biotechnology -Biophysics -Biology Education -Cellular Biology and Anatomical Sciences -Ecology, Evolution & Environment -Entomology -Forestry -General Biology -Genetics & Heredity -Life Sciences - Other topics -Microbiology and Immunology -Molecular Biology -Mycology -Palaeontology -Parasitology -Pharmacology & Pharmacy -Physiology and Related Sciences -Plant Sciences -Toxicology -Veterinary Sciences -Virology -Zoology
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