Breast Cancer in Young Nigerian Women

C. Ohanaka
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引用次数: 3

Abstract

Breast cancer is rare in young women aged 30 and below. Out of a total of 374 patients admitted and managed for breast cancer in a period of 12 years, 14 (3.74%) were aged 30 and below (mean 26.31 years); Their parity ranged between 0 and 4 (mean 1.5) and the duration of symptoms before presentation ranged between 3 weeks and 3 years. 6 cases involved the right breast, 4 the left and 3 were bilateral. All the patients presented with advanced breast cancer (stage 4 disease). Ten had invasive ductal Ca while one each had lobular carcinoma, lymphoma and malignant phyllodes tumour respectively. Management was multimodal: neovadjuvant chemotherapy, tamoxifen, mastectomy and referral for radiotherapy. Two developed features of depressive illness in the course of treatment; 6 died within 6 months of presentation, 1 after 3 months, 1 refused mastectomy discharged herself against in favour of traditional healers. The remaining 6 were lost to follow-up. It is confirmed that as else where, in Nigerians breast cancer in younger women is associated with a high degree of morbidity and mortality as well as physical and emotional stress. Keywords: Young women, breast cancer, Nigeria.Nigerian Journal of Surgical Sciences Vol. 17 (2) 2007: pp. 86-90
尼日利亚年轻妇女的乳腺癌
乳腺癌在30岁及以下的年轻女性中很少见。在12年期间,共有374名乳腺癌患者入院并接受治疗,其中14名(3.74%)年龄在30岁及以下(平均26.31岁);他们的胎次在0和4之间(平均1.5),症状出现前的持续时间在3周到3年之间。右乳6例,左乳4例,双乳3例。所有患者均为晚期乳腺癌(4期)。浸润性导管癌10例,小叶癌、淋巴瘤和恶性叶状瘤各1例。治疗是多模式的:新辅助化疗,他莫昔芬,乳房切除术和转诊放疗。抑郁症在治疗过程中出现的两个特征;6人在6个月内死亡,1人在3个月后死亡,1人拒绝乳房切除术,自己出院反对传统治疗师。其余6例未随访。经证实,在尼日利亚,与其他地方一样,年轻妇女的乳腺癌与高发病率和死亡率以及身体和精神压力有关。关键词:年轻女性,乳腺癌,尼日利亚。尼日利亚外科科学杂志Vol. 17 (2) 2007: pp. 86-90
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