Pediatric Clinical Features of Covid-19 in Cameroon

Meguieze Claude-Audrey, N. Eric, Mekone Nkwele Isabelle, Kalla Ginette Claude Mireille, Kamgaing Nelly, Ngo Nyeki Adèle-Rose, Onambele Paul, N. M. Carlin, Koki Ndombo Paul
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Abstract

Introduction: The Covid-19 pandemic is a public health emergency characterized by severe acute respiratory distress syndrome. It has many clinical forms and affects all age groups. Despite the magnitude of this pandemic, data from pediatric cohorts in Cameroon remain sparse. Objective: The aim of this study was to describe the clinical presentation of Covid-19 in the pediatric population of the Nkolndongo health district. Materials and method: A cross-sectional study was conducted for a duration of 5 months from January to May 2021 and covered a period of 9 months (March to December 2020). All patients aged 0 to 19 years, suspected of having Covid-19, confirmed by real-time RT-PCR targeting the N and ORF1 ab viral genes and managed in the Nkolndongo health district were included. The results were analyzed using IBM SPSS.23.0 software and the data expressed as frequencies, percentages, and means. The threshold of statistical significance was set at 0.05. Results: This study revealed that 48 patients out of 154 suspected cases were tested positive. The most affected age group was adolescents aged 13 19 years (92.85%). The most frequent symptoms were cough (33%), fever (42%) and nasal discharge (25%). Infants were the least affected. 58% of patients were asymptomatic, 47.91% were in mild stage, 8.33% in moderate stage and 4.16% in severe stage. All the children tested positive survived. Patients with comorbidity were 20 times more likely to develop moderate to severe clinical forms, this being statistically significant. Conclusion: The clinical presentation reported mainly fever, cough and anterior nasal discharge. There was a significant association between the presence of comorbidity and the moderate How to cite this paper: Claude-Audrey, M., Eric, N.E., Isabelle, M.N., Mireille, K.G.C., Nelly, K.N., Adèle-Rose, N.N., Paul, O., Carlin, N.M. and Paul, K.N. (2022) Pediatric Clinical Features of Covid-19 in Cameroon. Open Journal of Pediatrics, 12, 231237. https://doi.org/10.4236/ojped.2022.121025 Received: February 8, 2022 Accepted: March 20, 2022 Published: March 23, 2022 Copyright © 2022 by author(s) and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/ Open Access M. Claude-Audrey et al. DOI: 10.4236/ojped.2022.121025 232 Open Journal of Pediatrics to severe degrees of severity.
喀麦隆Covid-19的儿科临床特征
新冠肺炎大流行是一场以严重急性呼吸窘迫综合征为特征的突发公共卫生事件。它有许多临床表现,影响所有年龄组。尽管这次大流行的规模很大,但来自喀麦隆儿科队列的数据仍然很少。目的:本研究的目的是描述nkolndonggo卫生区儿科人群中Covid-19的临床表现。材料和方法:横断面研究于2021年1月至5月,为期5个月,为期9个月(2020年3月至12月)。所有年龄在0至19岁、疑似感染Covid-19、经针对N和ORF1 ab病毒基因的实时RT-PCR确诊并在nkolndonggo卫生区进行管理的患者均被纳入研究。使用IBM SPSS.23.0软件对结果进行分析,数据以频率、百分比和平均值表示。统计学显著性阈值设为0.05。结果:154例疑似病例中48例呈阳性。13 ~ 19岁的青少年是影响最大的年龄组(92.85%)。最常见的症状是咳嗽(33%)、发烧(42%)和流鼻水(25%)。婴儿受到的影响最小。无症状者占58%,轻度占47.91%,中度占8.33%,重度占4.16%。所有检测呈阳性的孩子都活了下来。有合并症的患者发展为中度至重度临床形式的可能性是其20倍,这具有统计学意义。结论:临床表现以发热、咳嗽、前鼻流为主。共病的存在与轻度感染之间存在显著关联。本文引文:Claude-Audrey, M., Eric, n.e., Isabelle, m.n., Mireille, K.G.C, Nelly, K.N., ad - rose, n.n., Paul, O., Carlin, N.M.和Paul, K.N.(2022)喀麦隆Covid-19的儿科临床特征。儿科杂志,12,231237。https://doi.org/10.4236/ojped.2022.121025收稿日期:2022年2月8日收稿日期:2022年3月20日出版日期:2022年3月23日版权所有©2022作者与科研出版公司。本作品采用知识共享署名国际许可协议(CC BY 4.0)。http://creativecommons.org/licenses/by/4.0/开放获取M. Claude-Audrey等。DOI: 10.4236/ojped.2022.121025 232开放儿科杂志严重程度的严重性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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