Deep Hyperthermia Applicators: Σ-60 or Σ-Eye?

D. Fatehi, G. Rhoon
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Abstract

Abstract Aim: The goal of this study was functional evaluation of two deep hyperthermia (DHT) applicators to know whether we can replace Σ-60 with Σ-Eye (or vice versa). Methods: Data of all 48 patients with locally advanced cervical cancer who were treated within both applicators were analyzed. No performance of the longitudinal SAR-steering (SAR: specific absorption rate) option of Σ-Eye was done; thus, Σ-Eye was used as an Σ-60 with a modified water-bolus and shape. Temperature and RF-power (RF: radio frequency) indices were analyzed. Additionally a subgroup-analysis was applied for subgroups, categorized for the reasons of switching between the two applicators. Results: Analysis demonstrated a significant difference for power indices as applied to the two applicators; however, no difference was seen for temperature indices. The subgroup analyses revealed that when we applied Σ-Eye the power indices were mildly higher than those for the Σ-60. Contrarily, in majority of the patients applying Σ-Eye, number of off-switches and total switch-off time were lower than those for Σ-60. For the largest subgroup patients treated within the Σ-Eye, all temperature indices were slightly lower (ΔT=0.2–0.5°C) than those for the Σ-60 (p<0.028). Conclusion: In case of severe patients discomfort for DHT applicator, or when we are not satisfactory for the achieved temperatures, one can freely switch between the Σ-60 and Σ-Eye or vice versa during a DHT treatment series without loss in quality of treatment.
深层热疗涂抹器:Σ-60或Σ-Eye?
摘要目的:本研究的目的是对两种深度热疗(DHT)应用器进行功能评估,以了解我们是否可以用Σ-Eye替代Σ-60(反之亦然)。方法:对48例局部晚期宫颈癌患者在两种涂抹器内治疗的资料进行分析。没有进行纵向SAR转向(SAR:比吸收率)Σ-Eye选项的性能测试;因此,Σ-Eye被用作修改了水丸和形状的Σ-60。分析了温度和射频功率(RF:射频)指标。此外,对子组进行亚组分析,根据在两种涂抹器之间切换的原因进行分类。结果:分析表明,两种涂抹器的功率指标有显著差异;然而,温度指数没有差异。亚组分析显示,当我们使用Σ-Eye时,功率指数略高于Σ-60。相反,大多数使用Σ-Eye的患者,关闭开关次数和总关闭时间低于Σ-60。对于在Σ-Eye内治疗的最大亚组患者,所有温度指标均略低于Σ-60 (p<0.028) (ΔT= 0.2-0.5°C)。结论:如果患者对DHT涂抹器感到严重不适,或者当我们对达到的温度不满意时,可以在DHT治疗系列中自由切换Σ-60和Σ-Eye,反之亦然,而不会影响治疗质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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